SP135
GENDER SPECIFIC ASSOCIATION BETWEEN WEIGHT CHANGE AND LOW SODIUM DIET BASED ON ESTIMATED 24 HR URINARY SODIUM EXCRETION IN KOREAN ADULTS WITH NON CHRONIC KIDNEY DISEASE

INTRODUCTION AND AIMS: High salt intake is associated with obesity. Gender-specific approach is needed to manage obesity because sex differences contribute to the development of obesity. We evaluated factors associated with low sodium diet according to gender and relationship between weight change and low sodium diet.

METHODS: This study analyzed data of 9426 non-CKD participants ≥18 years old who completed urinary sodium and creatinine evaluation in Korea National Health and Nutritional Examination Survey (2014 and 2015). The 24hr urine sodium excretion level was estimated using Tanaka equation. Low sodium diet was defined as 24hr urine sodium ≤2g/day. Weight change was classified as maintenance, loss, and gain for a year. Obesity was defined as body mass index(BMI) ≥25 kg/m².

RESULTS: Participants who consumed low sodium diet were 227 (5.5%) among 4165 male and 413 (7.9%) among 5261 female. Prevalence of obesity was 39.0% in male and 27.0% in female. In both gender groups, low sodium diet was associated with high serum creatinine, but not glomerular filtration rate. Low sodium diet did not show a statistically significant relationship with weight change for a year. Participants who tried to exercise, reduce or skip the meal, or fast to maintain or lose weight was not related with low sodium diet, except male subjects who tried to exercise. Table. Factors associated with low sodium diet according to gender (obtained by multivariate logistic regression analysis)*Multivariate logistic regression analysis was conducted with adjustment for metabolic syndrome, diastolic blood pressure (DBP), and fat intake in male group and ischemic heart disease, metabolic syndrome, menopause, weight change, DBP, fasting glucose, total cholesterol, fat intake, and carbohydrate intake in female group.

CONCLUSIONS: In non-CKD population ≥18 years old, low sodium intake was more prevalent in female and obesity was more prevalent in male. In male subjects, low sodium diet was related with young age, marital status, low BMI, and high serum creatinine. In female subjects, low sodium diet was associated with young age, marital status, low systolic blood pressure, low BMI, and high serum creatinine. Low sodium diet did not show a statistically significant relationship with weight change for a year, although low sodium diet was associated with low BMI. Among participants who tried to maintain or lose weight, most of participants was not related with low sodium intake. Education for effects of low sodium diet for prevention of obesity and policy-based interventions may be needed to manage obesity, especially for middle-aged and older married adults.