Introduction and Aims: Residual renal function (RRF) was found to be an important predictor of mortality and cardiovascular (CV) deaths in peritoneal dialysis (PD) patients, and contibutes more significantly to overall survival than PD clearance. We investigated correlation between RRF with parameters associated with CV outcomes in PD patients.
Methods: 190 PD patients from 13 dialysis centres were included in investigation. Biomarkers of anaemia, nutritional status (malnutrition inflammation score (MIS), subjective global assessment (SGA), serum albumins, body mass index (BMI), anthropometric measurements), dialysis dose (Kt/V) and laboratory measurements were determined. RRF was estimated as volume of daily urine.
Results: There were 78 (41.05 %) females and 112 (58.95 %) males; aged 57.35 ± 14.41 years, treated with PD for 24.96 ± 24.43 months. 56 patients had diabetes. The mean RRF was 1170±673,6 ml (range 0-3000 ml). Statistically significant correlations between RRF and BMI, hip circumference, time on PD, Kt/V, MIS, SGA, E, Hb, PTH, and serum albumins were found (Table 1).
Table 1. Statistically significant correlations between RRF and CV disease related parameters in PD patients (Pearson correlation coefficient, one-tailed significance level)
Conclusions: This study demonstrated significant correlation of RRF with numerous well known cardiovascular risk factors. Every effort should be invested to maintain RRF as long as possible to achieve optimal treatment results and to decrease CV mortality in PD population.
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