Extract

`It is easier to split an atom than a prejudice' (A. Einstein)

High blood pressure (BP) levels are unequivocally associated with increased risks of major cardiovascular events and stroke [1]. Significant progress in the control of hypertension over the years has also led to a true explosion of morbidity and mortality trials in hypertensive patients [2]. These studies have shown a significant reduction in the incidence of cardiovascular and cerebrovascular events. This has been obtained, almost without exception, with combinations of antihypertensive agents.

Despite the impressive results of the trials, most investigators document, even today, that BP continues to be poorly controlled in too many hypertensive patients [3,4]. This is not a new problem and the failure to control BP in many treated patients was observed several years ago (Table 1). It has been repeatedly confirmed that approximately 20–40% of patients fail to achieve the goal of treatment. A notable exception is represented by the results of the recently published HOT study, in which 18 790 patients from 26 countries were followed for 3–8 years. Satisfactory control of BP (<90 mmHg diastolic) was achieved in approximately 90% of treated patients [10].

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