Extract

Introduction

The incidence of mycobacteriae infections has grown rapidly over the last few years. In particular, non‐tuberculous mycobacteriae infections, especially those caused by Mycobacterium fortuitum and Mycobacterium chelonae, are becoming highly prevalent [1]. Several cases of peritonitis due to these organisms among patients receiving peritoneal dialysis (PD) have been described [2,3]. Although peritoneal catheter exit‐site infections are very rare [4–6], we report here five cases, one of which was complicated by peritonitis.

Cases

Case 1

A 61‐year‐old woman diagnosed with diabetes mellitus and hypertension started PD in August 1993 and progressed well until September 1994. At this time, she presented with a granuloma and purulent drainage from the catheter sinus. Drainage culture revealed Corynebacterium and Staphylococcus epidermidis, which were eradicated after treatment with vancomycin and mupirocin. Subsequently a purulent discharge appeared and all cultures were negative. Two acid‐fast stains, the last performed in June 1995, were also negative. Two months later the infection was accompanied by a peritonitis episode. At this time the peritoneal effluent and exit‐site drainage culture showed growth of M. chelonae. The peritoneal catheter was removed and the patient was treated for 2 months with varying combinations of antibiotics recommended by sensitivity testing (ciprofloxacin, clarithromycin and amikacin), she suffered from side effects including vomiting, hepatic alterations and anaemia. The patient refused to continue PD and was transferred to haemodialysis.

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