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Hsiann Y. Wang, Ja L. Lin, Trichosporon beigelii fungaemia in a patient with haemodialysis, Nephrology Dialysis Transplantation, Volume 14, Issue 8, August 1999, Pages 2017–2018, https://doi.org/10.1093/ndt/14.8.2017
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Introduction
Trichosporonosis is noted increasingly in immunocompromised and neutropenic patients. Disseminated trichosporonosis is a life-threatening condition. We observed systemic Trichosporon infection in a patient on maintenance haemodialysis.
Case
A 76-year-old male patient with a history of pulmonary tuberculosis, coronary artery disease and polycystic kidney disease with chronic renal insufficiency had been treated by maintenance haemodialysis three times per week for 3 months before admission. He had progressive loss of consciousness and intermittent low grade fever before he was admitted to a local hospital and treated with broad spectrum parenteral antibiotics for 2 weeks. His condition deteriorated and he was transferred to our hospital.
The initial physical examination revealed coma (Glasgow coma scale: E1M1V1), body temperature 37.8°C, heart rate 102 per min, respiration 16 per min, blood pressure 135/90 mm Hg. Haemoglobin was 8.3 g/dl, platelet 252×103/μl, white cell count 13600/μl, blood urea nitrogen 167 mg/dl, creatinine 7.1 mg/dl, calcium 8.4 mg/dl, phosphorus 6.6 mg/dl, sodium 133 mmol/l, and potassium 5.0 mmol/l. His initial chest X-ray showed no active lung lesion. On the 3rd day, `yeast-like' organisms were grown in blood cultures [1] and catheter tip cultures from the left femoral vein double lumen catheter which has been inserted 2 months previously. Sputum cultures were negative. The organism was identified as Trichosporon beigelii by microscopy (Figure 1). The patient was treated with amphotericin B (40 mg/day) in addition to parenteral antibiotics.
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