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High-Impact Research from Molecular Biology and Evolution
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Explore a collection of the most read and most cited articles making an impact in Molecular Biology and Evolution published within the past two years. This collection will be continuously updated with the journal's leading articles so be sure to revisit periodically to see what is being read and cited.
Also discover the articles being discussed the most on digital media by exploring this Altmetric report pulling the most discussed articles from the past year.
Most cited
Earl Grey: A Fully Automated User-Friendly Transposable Element Annotation and Analysis Pipeline
Tobias Baril and others
Molecular Biology and Evolution, Volume 41, Issue 4, April 2024, msae068, https://doi.org/10.1093/molbev/msae068

Major Revisions in Pancrustacean Phylogeny and Evidence of Sensitivity to Taxon Sampling
James P Bernot and others
Molecular Biology and Evolution, Volume 40, Issue 8, August 2023, msad175, https://doi.org/10.1093/molbev/msad175

Building Phylogenetic Trees From Genome Sequences With kSNP4
Barry G Hall and Jeremiah Nisbet
Molecular Biology and Evolution, Volume 40, Issue 11, November 2023, msad235, https://doi.org/10.1093/molbev/msad235

MEGA12: Molecular Evolutionary Genetic Analysis Version 12 for Adaptive and Green Computing
Sudhir Kumar and others
Molecular Biology and Evolution, Volume 41, Issue 12, December 2024, msae263, https://doi.org/10.1093/molbev/msae263

Dynamics of Gene Loss following Ancient Whole-Genome Duplication in the Cryptic Paramecium Complex
Jean-Francois Gout and others
Molecular Biology and Evolution, Volume 40, Issue 5, May 2023, msad107, https://doi.org/10.1093/molbev/msad107

Redefining Possible: Combining Phylogenomic and Supersparse Data in Frogs
Daniel M Portik and others
Molecular Biology and Evolution, Volume 40, Issue 5, May 2023, msad109, https://doi.org/10.1093/molbev/msad109

A Quantitative Theory for Genomic Offset Statistics
Clément Gain and others
Molecular Biology and Evolution, Volume 40, Issue 6, June 2023, msad140, https://doi.org/10.1093/molbev/msad140

Genetic Load and Adaptive Potential of a Recovered Avian Species that Narrowly Avoided Extinction
Georgette Femerling and others
Molecular Biology and Evolution, Volume 40, Issue 12, December 2023, msad256, https://doi.org/10.1093/molbev/msad256

Bivalves Present the Largest and Most Diversified Repertoire of Toll-Like Receptors in the Animal Kingdom, Suggesting Broad-Spectrum Pathogen Recognition in Marine Waters
Amaro Saco and others
Molecular Biology and Evolution, Volume 40, Issue 6, June 2023, msad133, https://doi.org/10.1093/molbev/msad133

Whole Genome Duplication and Gene Evolution in the Hyperdiverse Venomous Gastropods
Sarah Farhat and others
Molecular Biology and Evolution, Volume 40, Issue 8, August 2023, msad171, https://doi.org/10.1093/molbev/msad171

Most read
Research Article
The genomic study of specimens dating to the Early and Middle Pleistocene (EP and MP), a period spanning from 2.6 million years ago (Ma) to 126 thousand years ago (ka), has the potential to elucidate the evolutionary processes that shaped present-day biodiversity. Obtaining genomic data from this period is challenging, but ...
A Million Years of Mammoth Mitogenome Evolution
J Camilo Chacón-Duque and others
Molecular Biology and Evolution, Volume 42, Issue 4, April 2025, msaf065, https://doi.org/10.1093/molbev/msaf065

Research Article
We introduce the 12th version of the Molecular Evolutionary Genetics Analysis ( MEGA12 ) software. This latest version brings many significant improvements by reducing the computational time needed for selecting optimal substitution models and conducting bootstrap tests on phylogenies using maximum likelihood (ML) methods. ...
MEGA12: Molecular Evolutionary Genetic Analysis Version 12 for Adaptive and Green Computing
Sudhir Kumar and others
Molecular Biology and Evolution, Volume 41, Issue 12, December 2024, msae263, https://doi.org/10.1093/molbev/msae263

Research Article
The clade Pancrustacea, comprising crustaceans and hexapods, is the most diverse group of animals on earth, containing over 80% of animal species and half of animal biomass. It has been the subject of several recent phylogenomic analyses, yet relationships within Pancrustacea show a notable lack of stability. Here, the ...
Major Revisions in Pancrustacean Phylogeny and Evidence of Sensitivity to Taxon Sampling
James P Bernot and others
Molecular Biology and Evolution, Volume 40, Issue 8, August 2023, msad175, https://doi.org/10.1093/molbev/msad175

Review Article
Many commonly studied species now have more than one chromosome-scale genome assembly, revealing a large amount of genetic diversity previously missed by approaches that map short reads to a single reference. However, many species still lack multiple reference genomes and correctly aligning references to build pangenomes ...
K-mer-based Approaches to Bridging Pangenomics and Population Genetics
Miles D Roberts and others
Molecular Biology and Evolution, Volume 42, Issue 3, March 2025, msaf047, https://doi.org/10.1093/molbev/msaf047

Research Article
Genomic adaptation and introgression can occur during the speciation process, enabling species to diverge in their frequencies of adaptive alleles or acquire new alleles that may promote adaptation to environmental changes. There is limited information on introgression in organisms from extreme environments and their ...
Genomic Introgression and Adaptation of Southern Seabird Species Facilitate Recent Polar Colonization
Josefina Jorquera and others
Molecular Biology and Evolution, Volume 42, Issue 3, March 2025, msaf053, https://doi.org/10.1093/molbev/msaf053

Research Article
Phylogenetic inference aims at reconstructing the tree describing the evolution of a set of sequences descending from a common ancestor. The high computational cost of state-of-the-art maximum likelihood and Bayesian inference methods limits their usability under realistic evolutionary models. Harnessing recent advances in ...
Phyloformer: Fast, Accurate, and Versatile Phylogenetic Reconstruction with Deep Neural Networks
Luca Nesterenko and others
Molecular Biology and Evolution, Volume 42, Issue 4, April 2025, msaf051, https://doi.org/10.1093/molbev/msaf051

Research Article
Microorganisms endure novel challenges for which other microorganisms in other biomes may have already evolved solutions. This is the case of nosocomial bacteria under antibiotic therapy because antibiotics are of ancient natural origin and resistances to them have previously emerged in environmental bacteria. In such ...
The Spread of Antibiotic Resistance Is Driven by Plasmids Among the Fastest Evolving and of Broadest Host Range
Charles Coluzzi and Eduardo P C Rocha
Molecular Biology and Evolution, Volume 42, Issue 3, March 2025, msaf060, https://doi.org/10.1093/molbev/msaf060

Research Article
Rates of molecular evolution are known to vary across species, often deviating from the classical expectation of a strict molecular clock. In many cases, the rate of molecular evolution has been found to correlate to generation time, an effect that could be explained if species with shorter generation times have higher ...
Estimates of the Mutation Rate per Year Can Explain Why the Molecular Clock Depends on Generation Time
Loveday Lewin and Adam Eyre-Walker
Molecular Biology and Evolution, Volume 42, Issue 4, April 2025, msaf069, https://doi.org/10.1093/molbev/msaf069

Research Article
Kazakh people, like many other populations that settled in Central Asia, demonstrate an array of mixed anthropological features of East Eurasian (EEA) and West Eurasian (WEA) populations, indicating a possible scenario of biological admixture between already differentiated EEA and WEA populations. However, their complex ...
Ancestral Origins and Admixture History of Kazakhs
Chang Lei and others
Molecular Biology and Evolution, Volume 41, Issue 7, July 2024, msae144, https://doi.org/10.1093/molbev/msae144

Research Article
Invasive species pose significant threats to island ecosystems, often leading to the decline of native species and the disruption of ecological balance. The avian vampire fly ( Philornis downsi ), introduced to the Galápagos Islands of Ecuador, has emerged as a major threat to the endemic avifauna, parasitizing multiple ...
Genomic Insights into the Successful Invasion of the Avian Vampire Fly (Philornis downsi ) in the Galápagos Islands
Aarati Basnet and others
Molecular Biology and Evolution, Volume 42, Issue 3, March 2025, msaf052, https://doi.org/10.1093/molbev/msaf052
