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I would like to begin by thanking the people who have read this research at various stages of its development, all of whom have been generous with their time and advice. This includes Anne-Marie Beller, Pamela K. Gilbert and Marcus Waithe, with special thanks to Angela Wright for her support and encouragement. My gratitude also goes to the British Society for Literature and Science and the Victorian Popular Fiction Association; I have presented early drafts of several chapters at their annual conferences, and the feedback and suggestions from other delegates have been invaluable. The same goes for the Medical Humanities, Medicine and Literature seminar series at the University of Bristol; the Centre for Nineteenth-Century Studies at the University of Sheffield; the North-West Long Nineteenth-Century seminar series; and the Oxford Literature and Science seminar series, where I have been invited to share my work. I am also grateful to Andrew Mangham, Diane B. Paul and Catherine Delafield for sharing information, ideas and their work with me. My series editors, Anna Barton and Andrew Smith, have been so helpful, informative and patient, that I can only apologise for drawing on the latter quality quite as much as I have. Some of my very early work on Chapter 2 appeared in Leeds Working Papers in Victorian Studies (‘“She ought to have been a great man. Nature makes these mistakes now and then”: Right living in the wrong body in John Marchmont’s Legacy’), and some material from Chapters 3 and 5 has appeared in my article ‘Wilkie Collins’s monomaniacs in Basil, No Name and Man and Wife’, in the Wilkie Collins Journal; I am grateful to the editors for their kind permission to reprint it here. I would also like to thank my mother, Patricia Ifill, and Louise and Alan Pink, whose houses have acted as writing retreats for me at crucial moments. My eternal thanks as well to Phil Smith, who has always been willing to act as a sounding board, a proofreader, a critic and a cook as necessary.
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