Volume 73, Issue 6, 15 March 2022

Zn is a cofactor for countless processes and its accurate supply to cellular target sites represents a fundamental challenge. Underlying mechanisms controlling the dynamics of Zn pools in plant cells are poorly understood.

Zinc deficiency represents a major agronomic and health issue. Translating the massive knowledge acquired in Arabidopsis about zinc deficiency response mechanisms for biofortification of dicotyledonous crops is therefore paramount.

Following iron transport to leaves, proper control over its location and incorporation is required, while sensing of the organellar iron status is also crucial.

Post-transcriptional modulators of copper and iron metalloproteins establish a flexible ranking of protein metalation driven by the organelle signals under metal deficiency and stress conditions.

A comprehensive review of how the availability of essential trace metals modulates nutrient acquisition by altering the rhizosphere environment, interfering with uptake and signaling mechanisms, and shaping root systems.

We summarize current understanding of molybdate uptake and transport and discuss the potential role of molybdate transporter AtMOT1;1 in adaptation to local environments.

This work provides an overview of reciprocal interactions between trace metal homeostasis and heat stress responses in plants.

This review calls attention to the importance of plant micronutrient homeostasis for healthy nutrition of the growing human population, and for productive and sustainable agriculture, under increasing environmental constraints.

This review describes the transporters involved in the uptake, vacuolar sequestration, root-to-shoot translocation, and distribution of zinc in rice, and discusses how to balance optimal plant nutrition and human nutrition for zinc.

We review how the microbiota in the rhizosphere influence Fe uptake from soil, together with the process of loading Fe into seed, and consider how wild relatives provide a potential genetic resource for improvement of crops.

Despite the diversity of nanometal-induced hormetic effects, the application of nanometals in sustainable agriculture is promising, but should be preceded by detailed examination of plant responses using (multi)omics.