Extract

Objective

Men with stuttering priapism often experience almost daily prolonged and painful sleep-related erections. The aim of this study is to evaluate the clinical features and treatment options of this rare and poorly understood condition.

Methods

A cohort study of 133 men that attended outpatients or the emergency department at a tertiary andrology unit between 2004 and 2017. Data was collected retrospectively in 102 of the patients (seen and/or discharged between 2004 - 2015) and prospectively in 31 patients (Seen between 2015 – 2017). The effectiveness of each treatment option was classified into; no effect, partial response and complete remission. Many of the patients have tried more than one of the available treatments.

Results

Aetiological factors included haemoglobinopathy (n = 67) (sickle cell disease [SCD] and thalassemia), drugs (n = 8), neurogenic causes (n = 3) homocystinuria (n = 1), haemodialysis (n = 1), trauma (n = 1), following surgery (n = 1) and idiopathic (n = 51). The mean (SE) age of the patients in the cohort is was 40.5 (1.2) years and age at diagnosis was 30.8 (1.2) years. There was a significant (p = 0.0001) bimodal age distribution at diagnosis between men with and without a haemoglobinopathy (24.5 vs 37.4 years). Within this series, numerous treatment options were effective at reducing the number and length of priapism episodes and are highlighted in Table 1.

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