Synergic effect of combined intervention with clindamycin and PPARγ agonist in an HLA-II mouse model of Group A Streptococcal Necrotizing Fasciitis Get access

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Skin transcriptomics reveals novel insights into pathophysiological mechanisms in humanized mice models of Group A Streptococcal Necrotizing Soft Tissue Infections Get access

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Toxic Shock Syndrome: Characterization of Human Immune Responses to TSST-1 and Evidence for Sensitivity Thresholds Get access

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Systemic Dysregulation of Angiopoietin-1 and -2 in Streptococcal Toxic Shock Syndrome Get access

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Individual Genetic Variations Directly Effect Polarization of Cytokine Responses to Superantigens Associated with Streptococcal Sepsis: Implications for Customized Patient Care Get access

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Dissection of the Molecular Basis for Hypervirulence of an In Vivo—Selected Phenotype of the Widely Disseminated M1T1 Strain of Group A Streptococcus Bacteria Get access

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Molecular Requirements for MHC Class II α-Chain Engagement and Allelic Discrimination by the Bacterial Superantigen Streptococcal Pyrogenic Exotoxin C Get access

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Commercial peptidoglycan preparations are contaminated with superantigen-like activity that stimulates IL-17 production Get access

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Heat Shock Protein 90 Associates with Monarch-1 and Regulates Its Ability to Promote Degradation of NF-κB-Inducing Kinase Get access

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HLA Transgenic Mice Provide Evidence for a Direct and Dominant Role of HLA Class II Variation in Modulating the Severity of Streptococcal Sepsis Get access

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Modulation of Expression of Superantigens by Human Transferrin and Lactoferrin: A Novel Mechanism in Host-Streptococcus Interactions Get access

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Human Lymphoid and Myeloid Cell Development in NOD/LtSz-scid IL2Rγ^null Mice Engrafted with Mobilized Human Hemopoietic Stem Cells^, Get access

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Selective Modulation of Superantigen-Induced Responses by Streptococcal Cysteine Protease Get access

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Evidence for Superantigen Involvement in Severe Group A Streptococcal Tissue Infections Get access

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Relative Neutralizing Activity in Polyspecific IgM, IgA, and IgG Preparations against Group A Streptococcal Superantigens Get access

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Intravenous Immunoglobulin Therapy for Streptococcal Toxic Shock Syndrome—A Comparative Observational Study Get access

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Varying Titers of Neutralizing Antibodies to Streptococcal Superantigens in Different Preparations of Normal Polyspecific Immunoglobulin G: Implications for Therapeutic Efficacy Get access

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Reply Get access

Selective Depletion Of Vβ-Bearing T Cells In Patients With Severe Invasive Group A Streptococcal Infections And Streptococcal Toxic Shock Syndrome Get access

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Metabolically active antigen presenting cells are required for human T cell proliferation in response to the superantigen streptococcal M protein Free

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