Extract

Multimodality in imaging compassing different techniques integrated for obtaining specific images from one object which contain not only complementary and comprehensive information about molecular processes, architecture and morphological state within the cells and tissues but also concomitant information of anatomy and functionalities of the object. The purposes of our research is to exploit the advantage in resolution limit of cathodoluminescence electron microscopy, the deep penetration emissions through biological tissue in near infrared (NIR) region and anatomical imaging MRI in order to established an multimodal imaging technique which cover wide range from nano- to meter-scale. In this work, we develop a combination of trimodal - tricolor imaging by using lanthanides (Tm 3+ , Er 3+ , Ho 3+ and Yb 3+ ) doped Gd 2 O 3 nanophosphors synthesized by homogenous precipitation method. The three colours CL emission under electron beam bombardment; NIR spectra (Fig) and cellular images under 980nm excitation were confirmed. T1 relaxations of the Gd 2 O 3 -nanophosphors in MRI at 11.7T are determined

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