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Journal Article
ACCEPTED MANUSCRIPT
Chinese Herbal Extracts Mediated Programmed Cell Death in Cancer and Inflammation Therapy Get access
Journal of Leukocyte Biology, qiaf051, https://doi.org/10.1093/jleuko/qiaf051
Published: 02 May 2025
Journal Article
ACCEPTED MANUSCRIPT
Secretory IgA binding to FCRL3 triggers shared inflammatory cytokine secretion by human regulatory T cells and effector T cells Get access
Journal of Leukocyte Biology, qiaf054, https://doi.org/10.1093/jleuko/qiaf054
Published: 02 May 2025
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Examination of T-cell subsets in sepsis. A) The gating strategy of T-cell s... Get access
Published: 25 April 2025
Fig. 1.
Examination of T-cell subsets in sepsis. A) The gating strategy of T-cell subsets. B) Absolute cell counts of CD4 + T cells, CD8 + T cells, and γδ T cells in patients with sepsis ( n = 20) and healthy controls ( n = 20) were analyzed by flow cytometry. * P < 0.05, ** P < 0.01.
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The alteration of percentage of peripheral CD57+γδ T cells in se... Get access
Published: 25 April 2025
Fig. 3.
The alteration of percentage of peripheral CD57 + γδ T cells in sepsis. A) The percentage of peripheral CD57 + γδ T cells was measured by flow cytometry in peripheral blood samples collected from 80 patients with sepsis and 80 healthy controls. B) The percentage of peripheral CD57 + γδ T cells were
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CD69 expression on NK cells after co-culture with hAECs differed in the stu...
Published: 25 April 2025
Fig. 4.
CD69 expression on NK cells after co-culture with hAECs differed in the study groups. A) The histogram displays the expression level of CD69 on the cell surface. The expression of CD69 on the surface of NK cells in the healthy group at 24 and 72 h and in the RSA group at 72 h after co-culture with h
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The expression changes in the expression of HLA-G, TGF-β,...
Published: 25 April 2025
Fig. 8.
The expression changes in the expression of HLA-G , TGF-β , and IL-10 genes in hAECs after 24 and 72 h of co-culture with NK cells. The baseline of the gene expression in negative control wells of hAECs is considered a calibrator. HLA-G gene expression was significantly decreased at 1:1 and 2:
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The changes of the concentration of the TGF-β, IL-10, and IFN-γ cytokines i...
Published: 25 April 2025
Fig. 10.
The changes of the concentration of the TGF-β, IL-10, and IFN-γ cytokines in the RSA and healthy groups at 24 and 72 h. There were no meaningful differences between study groups at cellular ratios (A) or time intervals (B). In the 24-h co-culture, the IL-10 concentration did not indicate a significa
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Ex vivo expansion alters expression of homing molecules on OT-I CD8 T cells... Get access
Published: 25 April 2025
Fig. 2.
Ex vivo expansion alters expression of homing molecules on OT-I CD8 T cells. A) Representative pseudocolor plots showing the forward and side scatter and the expression of CD62L and CD44 of CD8 OT-I T cells before (left) and after 7 d of ex vivo expansion (right). B, C) Expression of B) integrin sub
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Changes in CCR5, CXCR3, and CXCR6 ligand concentrations after MCMV infectio... Get access
Published: 25 April 2025
Fig. 5.
Changes in CCR5, CXCR3, and CXCR6 ligand concentrations after MCMV infection in Rag2 −/− γC −/− mice. The concentrations of A) CCR5 ligands CCL3, CCL4, and CCL5, B) CXCR3 ligand CXCL10, and c) CXCR6 ligand CXCL16 determined using Luminex assay (R&D Systems). Data are from 2 experiments and ar
Journal Article
ACCEPTED MANUSCRIPT
The release of NETs during SFTSV infection downregulates the specific inflammatory factors that lead to liver and spleen damage Get access
Journal of Leukocyte Biology, qiaf053, https://doi.org/10.1093/jleuko/qiaf053
Published: 25 April 2025
Journal Article
Different behavior of NK cells isolated from healthy women and women with recurrent spontaneous abortion after treatment with human amniotic epithelial cells
Journal of Leukocyte Biology, Volume 117, Issue 4, April 2025, qiaf020, https://doi.org/10.1093/jleuko/qiaf020
Published: 25 April 2025
Journal Article
Depression-like behavior is associated with changes in the meningeal lymphatic vasculature and meningeal B cells in a murine lupus model Get access
Journal of Leukocyte Biology, Volume 117, Issue 4, April 2025, qiaf016, https://doi.org/10.1093/jleuko/qiaf016
Published: 25 April 2025
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Domain structures of NLRP3 inflammasome proteins. 19 a) The NLR... Get access
Published: 25 April 2025
Fig. 1.
Domain structures of NLRP3 inflammasome proteins. 19 a) The NLRP3 protein consists of PYDs, a NACHT domain, which includes an NBD, HD1, WHD, and HD2, as well as an LRR domain. b) The ASC protein is composed of a PYD domain and a CARD. c) Caspase-1 comprises a CARD domain, a p20 subunit, and a p10
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The change of transcriptome of γδ T cells in sepsis. A) Overview of our seq... Get access
Published: 25 April 2025
Fig. 2.
The change of transcriptome of γδ T cells in sepsis. A) Overview of our sequencing workflow (sepsis, n = 3; HC, n = 3). B) Hierarchical clustering heatmap of DEGs in γδ T cells between sepsis and HC groups. C) Volcano plot showing differential gene expression in γδ T cells between sepsis and HC
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The expression signature of costimulatory molecules and activation markers ... Get access
Published: 25 April 2025
Fig. 4.
The expression signature of costimulatory molecules and activation markers within the CD57 + γδ T-cell subset. A) Expression levels (%) of costimulatory molecules on CD57 − and CD57 + γδ T cells. Patients with sepsis, n = 10; Healthy controls, n = 10. B) Expressions levels (%) of activation mar
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Cytotoxicity of CD57+γδ T-cell subset in sepsis. A) CD107a degra... Get access
Published: 25 April 2025
Fig. 6.
Cytotoxicity of CD57 + γδ T-cell subset in sepsis. A) CD107a degranulation in γδ T cells were compared between patients with sepsis ( n = 5) and healthy controls ( n = 5). The percentages of CD107a + cells in γδ T cells were analyzed by flow cytometry. B) The ratios of CD107a + cells in CD57 +
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Differences in the population of CD56dimCD16+ NK cell...
Published: 25 April 2025
Fig. 3.
Differences in the population of CD56 dim CD16 + NK cells in the study groups; A) In the 24-h co-cultures, the percentage of CD56 dim CD16 + cell population was significantly higher in the RSA group compared to the healthy group, but the difference between the 2 study groups decreased after 72 h
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Comparison of FasL expression on NK cells after co-culture with hAECs betwe...
Published: 25 April 2025
Fig. 5.
Comparison of FasL expression on NK cells after co-culture with hAECs between the study groups; A) the histogram reveals the expression level of FasL on the NK cells' surface. As a result of the co-culture in the healthy and RSA groups, the expression of FasL significantly increased (n = 20). B) Fas
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CD107a expression on the surface of NK cells in the RSA group was significa...
Published: 25 April 2025
Fig. 6.
CD107a expression on the surface of NK cells in the RSA group was significantly higher compared to the healthy group. A) The histogram shows the expression level of CD107a. The expression of CD107a on the surface of NK cells isolated from women with RSA significantly decreased after 24 and 72 h of c
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Changes in the concentrations of TGF-β (A) and IL-10 (B) cytokines in the s...
Published: 25 April 2025
Fig. 9.
Changes in the concentrations of TGF-β (A) and IL-10 (B) cytokines in the supernatant of co-culture and negative control wells at 24 and 72 h of incubation (n = 20). The highest concentration of TGF-β and IL-10 in study groups was observed at the 1:1 cellular ratio. TGF-β, transforming growth factor
