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Meeting Cluster Issue: Society for Leukocyte Biology (SLB) Conference 2022

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October 26-29, 2022, Waikoloa, Hawaii

Editors-in-Chief: Luis Montaner

Guest Editors: Dom Mavilio, Silvia Uriarte, Xin Chen

Effect of ethanol exposure on innate immune response in sepsis
Sanjoy Roychowdhury and others
Journal of Leukocyte Biology, Volume 115, Issue 6, June 2024, Pages 1029–1041, https://doi.org/10.1093/jleuko/qiad156
Ethanol exposure dysregulates innate immune response in sepsis.
VISTA nonredundantly regulates proliferation and CD69low γδ T cell accumulation in the intestine in murine sepsis
Chyna C Gray and others
Journal of Leukocyte Biology, Volume 115, Issue 6, June 2024, Pages 1005–1019, https://doi.org/10.1093/jleuko/qiad149
In this study, we found that VISTA nonredundantly regulates the proliferation and abundance of a CD69low γδ T cell population in murine lymphoid compartments.
Deficiency of macrophage-derived Dnase1L3 causes lupus-like phenotypes in mice
Minal Engavale and others
Journal of Leukocyte Biology, Volume 114, Issue 6, December 2023, Pages 547–556, https://doi.org/10.1093/jleuko/qiad115
Secretion of the endonuclease Dnase1L3 by macrophages limits lupus because its loss from macrophages induces autoantibodies, including anti-double-stranded DNA antibodies. Myeloid-derived DnaselL3 limits serum lupus phenotypes.
Proliferation of monocytes and macrophages in homeostasis, infection, injury, and disease
Jingbo Pang and Timothy J Koh
Journal of Leukocyte Biology, Volume 114, Issue 6, December 2023, Pages 532–546, https://doi.org/10.1093/jleuko/qiad093
In this review, we summarize historical and current evidence for, and provide perspective on, the proliferation of monocytes and macrophages in different tissues during homeostasis, infection, injury, and disease.
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