Volume 50, Issue 10, October 2020

Immune checkpoint inhibitors play a crucial role in the strategy for treating squamous cell carcinoma of the head and neck.

This review article summarized the evidence and on-going clinical trials of bladder preservation therapy for muscle invasive bladder cancer in the past and future immuno-oncology era.

Metastatic patient-derived xenograft mouse models for colorectal cancer were established with shorter time and higher success rate. And they retained the dominant characters of the original patient tumours.

Gene mutations of 63 cholangiocarcinoma patients were evaluated. We found that intrahepatic cholangiocarcinoma frequently occurred in young patients, and BAP1 and LRP2 could be biomarkers for Chinese intrahepatic cholangiocarcinoma patients.

With decreased smoking rates and aging of the population, lung cancer screening may be better targeted to a smaller at-risk population.

We developed and externally validated a Super learner-based model for patients with Stage I–III colorectal cancer, which could provide the probability of death from colorectal cancer in patients with resected colorectal cancer.

Lymphocyte-to-C-reactive protein ratio, a novel immune inflammation-based score (IBS), superior to other IBS, could more accurately predict post-operative morbidity and prognosis of gastric cancer.

The para-aortic lymph node evaluation was not associated with better survival in patients with International Federation of Gynecology and Obstetrics IIIC1p cervical cancer who were clinically para-aortic lymph node-negative.

We retrospectively investigated the institution’s outpatient flexible hysteroscopy cases. It is highly safe, with a slight negligible effect on ascites cytology. However, the diagnosis should be determined by multidisciplinary approaches.

Surveillance of the head and neck regions after endoscopic resection of esophageal cancer is required to detect second primary head and neck cancers at an early stage, thereby facilitating a minimally invasive treatment.

This study investigated the actual status of the utilization of such services and examined the related factors of their use using the transtheoretical model.

We evaluated our SBRT treatment results for patients with early-stage NSCLC using two different motion management systems. We have not found any difference in treatment outcomes in the whole cohort. Interestingly, we found that beam-on time might significantly affect treatment outcomes.

A national survey on the current status of for hormone-naïve prostate cancer with bone metastases identified radiation oncologists’ attitudes and practice patterns of radiotherapy in Japan.

Pulmonary epithelioid hemangioendothelioma showed three computed tomography patterns: multiple small nodules pattern, multiple nodules with large lesions pattern and single lesion pattern. Patients with pulmonary epithelioid hemangioendothelioma have good prognosis.

The mean age of testicular germ cell tumor patients is nearly 40 years. The proportion of older testicular germ cell tumor patients and testicular lymphoma patients was higher than previously thought.

This trial aimed to confirm the superiority of anatomical segmentectomy over wedge resection in terms of overall survival in high-risk operable patients with clinical stage IA non-small cell lung cancer.

Lung adenocarcinoma arising in a Li–Fraumeni syndrome patient, bearing germline mutation, R333Vfs^*12 of TP53, is sensitive to epidermal growth factor receptor-tyrosine kinase inhibitors, such as gefitinib and osimertinib.

Lifetime cumulative mortality risks differed greatly according to smoking status. The results of this study may be useful for the development of tailored prevention programs.