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Lei Pei, Jan-Ingmar Flock, Functional Study of Antibodies against a Fibrogenin-Binding Protein in Staphylococcus epidermidis Adherence to Polyethylene Catheters, The Journal of Infectious Diseases, Volume 184, Issue 1, 1 July 2001, Pages 52–55, https://doi.org/10.1086/321003
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Abstract
Staphylococcus epidermidis is an important pathogen in foreign body–associated infections. In a previous study, we showed that a surface-located fibrinogen-binding protein, termed Fbe, from S. epidermidis mediated the bacterial adherence to fibrinogen-coated surfaces in vitro. In the present study, we demonstrate that antibodies against Fbe can block adherence of S. epidermidis to fibrinogen-coated catheters, subcutaneously implanted catheters from rats, and peripheral venous catheters from human patients