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Bruce H. Hamory, Merle A. Sande, Austin Sydnor, Daniel L. Seale, Jack M. Gwaltney, Etiology and Antimicrobial Therapy of Acute Maxillary Sinusitis, The Journal of Infectious Diseases, Volume 139, Issue 2, February 1979, Pages 197–202, https://doi.org/10.1093/infdis/139.2.197
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Abstract
Eighty-one adults with symptoms of acute sinusitis were studied by direct needle puncture and aspiration of the maxillary sinus (105 sinuses). Fifty-nine bacterial strains were isolated in titers of ⩾104 colony-forming units/ml; Streptococcus pneumoniae and Haemophilus influenzae accounted for 64% of the isolates. Other bacteria recovered included anaerobes (12%), Neisseria species (8.5%), Streptococcus pyogenes (3%), α-hemolytic Streptococcus (3%), non-group A β-hemolytic Streptococcus (3%), Staphylococcus aureus (2%), Pseudomonas aeruginosa (2%), and Escherichia coli (2%), Viruses were isolated from 11 sinuses; these isolates included rhinovirus (six). influenza A (H3N2) virus (three), and two types of parainfluenza virus (one each). The efficacy of therapy with orally administered ampicillin. amoxicillin, or trimethoprim-sulfamethoxazole was evaluated by a repeat sinus puncture and culture. Clinical and bacteriologic responses to all three regimens were good.
- amoxicillin
- ampicillin
- pseudomonas aeruginosa
- streptococcus pyogenes
- staphylococcus aureus
- haemophilus influenzae
- adult
- maxillary sinusitis
- needles
- neisseria
- paracentesis
- paranasal sinuses
- rhinovirus
- streptococcus
- streptococcus pneumoniae
- trimethoprim-sulfamethoxazole combination
- bacteria
- bacteriology
- influenzavirus a
- maxillary sinus
- viruses
- parainfluenza virus
- antimicrobials
- escherichia coli
- sinusitis, acute
- causality