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Amila Patel, Julie Patel, Judy Ikwuagwu, Treatment of progressive multifocal leukoencephalopathy and idiopathic CD4+ lymphocytopenia, Journal of Antimicrobial Chemotherapy, Volume 65, Issue 12, December 2010, Pages 2489–2492, https://doi.org/10.1093/jac/dkq389
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Abstract
Progressive multifocal leukoencephalopathy is a neurological disease caused by the human polyoma virus JC virus and can present in patients with known immunodeficiencies. However, when associated with idiopathic CD4+ lymphocytopenia, management of patients can be quite challenging as these are two rare diseases with limited effective treatment options. In conjunction with the case report of a patient diagnosed with both conditions presented within this issue, a discussion of available treatment strategies is detailed.