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Jean Klastersky, Why empirical therapy?, Journal of Antimicrobial Chemotherapy, Volume 63, Issue suppl_1, May 2009, Pages i14–i15, https://doi.org/10.1093/jac/dkp075
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Abstract
Why empirical therapy? Because it works! Empirical antimicrobial therapy is a reasonable, pragmatic approach to limit the ominous threat of Gram-negative sepsis in febrile neutropenic cancer patients. Empirical treatment of occult fungal infection in patients with neutropenia and persistent fever, in spite of initial broad-spectrum antimicrobial coverage, is effective but the role of pre-emptive treatment remains to be established.
© The Author 2009. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: [email protected]
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