-
Views
-
Cite
Cite
Laurent Peyrin-Biroulet, Magnetic resonance imaging for Crohn's disease: Is this really the end of colonoscopy?, Inflammatory Bowel Diseases, Volume 16, Issue 7, 1 July 2010, Pages 1263–1264, https://doi.org/10.1002/ibd.21141
Close - Share Icon Share
Extract
Rimola J, Rodriguez S, García-Bosch O, et al. Magnetic resonance for assessment of disease activity and severity in ileocolonic Crohn's disease. Gut. 2009;58:1113–1120.
Rimola et al conducted a cross-sectional study to evaluate the accuracy of magnetic resonance imaging (MRI) in assessing disease activity and severity in Crohn's disease (CD). Between June 2007 and April 2008, 50 patients with clinically active (n = 35) or inactive (n = 15) CD were prospectively enrolled in a single-center study. Two validated tools, C-reactive protein and the Harvey–Bradshaw score, were used to assess clinical disease activity. All patients also underwent ileocolonoscopy and MRI within 2 days. Ileocolonoscopy was considered the reference standard for disease extent and severity. Endoscopic activity was evaluated with the Crohn's Disease Endoscopic Index of Severity (CDEIS). Hence, the variables used to assess the severity of endoscopic lesions were: ulcers (deep or superficial), ulcerated surface and affected surface, and stenosis (ulcerated or not). In addition, endoscopic lesions were classified as absent, mild (inflammation without ulcers), or severe (presence of ulceration). Complete endoscopic evaluation of the colon with intubation of the ileum was achieved in 36 (72%) patients. The total number of colonic segments examined was 213. All MR examinations were performed using a 3.0T MR unit. For both endoscopic and MRI evaluation, the intestine was divided into 6 segments: distal ileum, ascending, transverse, descending, sigmoid colon, and rectum.
