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Most Read Articles

See what your peers are reading! The EP Europace editors invite you to read the top 20 most read articles published within the past 12 months. This page is automated to reflect current readership, so bookmark this page and check back often to stay up-to-date with recent changes.

Discover most read articles from the ESC Journal family

European Society of Cardiology (ESC) clinical consensus statement on indications for conduction system pacing, with special contribution of the European Heart Rhythm Association of the ESC and endorsed by the Asia Pacific Heart Rhythm Society, the Canadian Heart Rhythm Society, the Heart Rhythm Society, and the Latin American Heart Rhythm Society
Michael Glikson and others
EP Europace, Volume 27, Issue 4, April 2025, euaf050, https://doi.org/10.1093/europace/euaf050
Conduction system pacing (CSP) is being increasingly adopted as a more physiological alternative to right ventricular and biventricular pacing. Since the 2021 European Society of Cardiology pacing guidelines, there has been growing evidence that this therapy is safe and effective. Furthermore, left bundle branch area ...
Practical Compendium of Antiarrhythmic Drugs: A Clinical Consensus Statement of the European Heart Rhythm Association of the ESC
Jose L Merino and others
The EHRA Practical Compendium of Antiarrhythmic Drugs (AADs) offers advice on these drugs, focusing on their clinical use and the global impact of cardiac arrhythmias. This document aims to provide practical instructions to clinicians in arrhythmia management through pharmacological strategies. The compendium highlights ...
Epicardial ventricular arrhythmia ablation: a clinical consensus statement of the European Heart Rhythm Association of the European Society of Cardiology and the Heart Rhythm Society, the Asian Pacific Heart Rhythm Society, the Latin American Heart Rhythm Society, and the Canadian Heart Rhythm Society
Arash Arya and others
EP Europace, Volume 27, Issue 4, April 2025, euaf055, https://doi.org/10.1093/europace/euaf055
Epicardial access during electrophysiology procedures offers valuable insights and therapeutic options for managing ventricular arrhythmias (VAs). The current clinical consensus statement on epicardial VA ablation aims to provide clinicians with a comprehensive understanding of this complex clinical scenario. It offers ...
Biventricular vs. right ventricular pacing devices in patients anticipated to require frequent ventricular pacing (BioPace)
Reinhard C Funck and others
EP Europace, Volume 27, Issue 3, March 2025, euaf029, https://doi.org/10.1093/europace/euaf029
Aims Right ventricular (RV) pacing may promote left ventricular (LV) dysfunction. Particularly in patients with preserved LV ejection fraction (LVEF), narrow QRS, and anticipated high ventricular pacing burden (HVPB), evidence is missing that biventricular (BiV) pacing can improve clinical outcome. We therefore evaluated ...
The diagnostic role of pharmacological provocation testing in cardiac electrophysiology: a clinical consensus statement of the European Heart Rhythm Association and the European Association of Percutaneous Cardiovascular Interventions (EAPCI) of the ESC, the ESC Working Group on Cardiovascular Pharmacotherapy, the Association of European Paediatric and Congenital Cardiology (AEPC), the Paediatric & Congenital Electrophysiology Society (PACES), the Heart Rhythm Society (HRS), the Asia Pacific Heart Rhythm Society (APHRS), and the Latin American Heart Rhythm Society (LAHRS)
Elijah R Behr and others
EP Europace, Volume 27, Issue 4, April 2025, euaf067, https://doi.org/10.1093/europace/euaf067
The pharmacological provocation test is a pivotal tool in cardiac electrophysiology for the diagnosis of potential causes of sudden cardiac death, sudden cardiac arrest (SCA), arrhythmias, symptoms, or ECG abnormalities. The 2022 European Society of Cardiology Guidelines for the Treatment of Ventricular Arrhythmias and ...
Ventricular arrhythmias in acute heart failure: a clinical consensus statement of the Association for Acute CardioVascular Care, the European Heart Rhythm Association, and the Heart Failure Association of the European Society of Cardiology
Bulent Gorenek and others
EP Europace, Volume 26, Issue 10, October 2024, euae235, https://doi.org/10.1093/europace/euae235
Patients presenting with or alerting emergency networks due to acute heart failure (AHF) form a diverse group with a plethora of symptoms, risks, comorbidities, and aetiologies. During AHF, there is an increased risk of destabilizing the functional substrate and modulatory adding to the risk of ventricular arrhythmias ...
Aggressive ablation vs. regular ablation for persistent atrial fibrillation: a multicentre real-world cohort study
Kaige Li and others
EP Europace, Volume 27, Issue 3, March 2025, euaf045, https://doi.org/10.1093/europace/euaf045
Aims Current guidelines for the optimal ablation strategy for persistent atrial fibrillation (PerAF) remain unclear. While our previous RCT confirmed the favourable prognosis of aggressive ablation, real-world evidence is still lacking. Methods and results Among 4833 PerAF patients undergoing catheter ablation at 10 ...
Cardioneuroablation for the treatment of reflex syncope and functional bradyarrhythmias: A Scientific Statement of the European Heart Rhythm Association (EHRA) of the ESC, the Heart Rhythm Society (HRS), the Asia Pacific Heart Rhythm Society (APHRS) and the Latin American Heart Rhythm Society (LAHRS)
Tolga Aksu and others
EP Europace, Volume 26, Issue 8, August 2024, euae206, https://doi.org/10.1093/europace/euae206
Cardioneuroablation has emerged as a potential alternative to cardiac pacing in selected cases with vasovagal reflex syncope, extrinsic vagally induced sinus bradycardia-arrest or atrioventricular block. The technique was first introduced decades ago, and its use has risen over the past decade. However, as with any ...
Identifying extra pulmonary vein targets for persistent atrial fibrillation ablation: bridging advanced and conventional mapping techniques
Alexander J Sharp and others
EP Europace, Volume 27, Issue 4, April 2025, euaf048, https://doi.org/10.1093/europace/euaf048
Aims Advanced technologies such as charge density mapping (CDM) show promise in guiding adjuvant ablation in patients with persistent atrial fibrillation (AF); however, their limited availability restricts widespread adoption. We sought to determine whether regions of the left atrium containing CDM-identified pivoting and ...
Atrial cardiomyopathy revisited—evolution of a concept: a clinical consensus statement of the European Heart Rhythm Association (EHRA) of the ESC, the Heart Rhythm Society (HRS), the Asian Pacific Heart Rhythm Society (APHRS), and the Latin American Heart Rhythm Society (LAHRS)
Andreas Goette and others
EP Europace, Volume 26, Issue 9, September 2024, euae204, https://doi.org/10.1093/europace/euae204
Aims The concept of “atrial cardiomyopathy” (AtCM) had been percolating through the literature since its first mention in 1972. Since then, publications using the term were sporadic until the decision was made to convene an expert working group with representation from four multinational arrhythmia organizations to prepare ...
PULSE survey: Population Survey on Knowledge, Gaps and Perception of Heart Rhythm disorders—an initiative of the Scientific Initiatives Committee of the European Heart Rhythm Association
Melanie A Gunawardene and others
EP Europace, Volume 27, Issue 4, April 2025, euaf032, https://doi.org/10.1093/europace/euaf032
Aims Despite increasing prevalence, the general population lacks knowledge regarding diagnosis, implications, and management of cardiac arrhythmias (CA). This study aims to assess public perception of CA and identify knowledge gaps. Methods and results The 36-item PULSE survey was disseminated via social media to the ...
Spotlight on the 2024 ESC/EACTS management of atrial fibrillation guidelines: 10 novel key aspects
Michiel Rienstra and others
EP Europace, Volume 26, Issue 12, December 2024, euae298, https://doi.org/10.1093/europace/euae298
Atrial fibrillation (AF) remains the most common cardiac arrhythmia worldwide and is associated with significant morbidity and mortality. The European Society of Cardiology (ESC)/European Association for Cardio-Thoracic Surgery (EACTS) have recently released the 2024 guidelines for the management of AF. This review ...
State-of-the-art pulsed field ablation for cardiac arrhythmias: ongoing evolution and future perspective
Kyoung-Ryul Julian Chun and others
EP Europace, Volume 26, Issue 6, June 2024, euae134, https://doi.org/10.1093/europace/euae134
Pulsed field ablation (PFA) is an innovative approach in the field of cardiac electrophysiology aimed at treating cardiac arrhythmias. Unlike traditional catheter ablation energies, which use radiofrequency or cryothermal energy to create lesions in the heart, PFA utilizes pulsed electric fields to induce irreversible ...
Safety and Effectiveness of the First Balloon-in-Basket Pulsed Field Ablation System for the Treatment of Atrial Fibrillation: VOLT CE Mark Study 6-Month Results
Roland R Tilz and others
Aims Pulsed field ablation (PFA) is a growing ablation modality for pulmonary vein isolation (PVI) in atrial fibrillation (AF) patients. This study assesses the 6-month safety and effectiveness of a novel balloon-in-basket, mapping-integrated PFA system, with a purpose-built form factor for PVI. Methods and Results The ...
Global burden of atrial fibrillation/atrial flutter and its attributable risk factors from 1990 to 2021
Siyuan Cheng and others
EP Europace, Volume 26, Issue 7, July 2024, euae195, https://doi.org/10.1093/europace/euae195
Aims To devise effective preventive measures, a profound understanding of the evolving patterns and trends in atrial fibrillation (AF) and atrial flutter (AFL) burdens is pivotal. Our study was designed to quantify the burden and delineate the risk factors associated with AF and AFL across 204 countries and territories ...
State of the Art of Artificial Intelligence in Clinical Electrophysiology in 2025. A Scientific Statement of the European Heart Rhythm Association (EHRA) of the ESC, the Heart Rhythm Society (HRS), and the ESC Working Group in e-Cardiology
E Svennberg and others
Aim Artificial Intelligence (AI) has the potential to transform cardiac electrophysiology (EP), particularly in arrhythmia detection, procedural optimization, and patient outcome prediction. However, a standardized approach to reporting and understanding AI-related research in EP is lacking. This scientific statement aims ...
How harmful is right ventricular pacing? The question revived by the BioPace trial
Mads Brix Kronborg and others
EP Europace, Volume 27, Issue 3, March 2025, euaf005, https://doi.org/10.1093/europace/euaf005
This issue of Europace presents the results of the Biventricular Pacing for atrioventricular Block to Prevent Cardiac Desynchronization (BioPace) trial. The main findings of the completed BioPace trial were presented as a late breaking clinical trial and abstract over 10 years ago. Now, the full data are available to ...
Pathophysiological aspects of carotid sinus massage: Cardioinhibition and vasodepression occur independent, respond differently to massage duration, and evoke corrective blood pressure responses
J Gert van Dijk and others
EP Europace, Volume 27, Issue 4, April 2025, euaf047, https://doi.org/10.1093/europace/euaf047
Aims We studied the blood pressure (BP) decrease after carotid sinus massage to study cardioinhibition (CI) and arterial vasodepression (aVD), whether CI and aVD occur independent of one another, and how the BP decrease ends. Methods and results We measured BP, heart rate (HR), stroke volume, and total peripheral ...
Management of patients with transvalvular right ventricular leads undergoing transcatheter tricuspid valve interventions. A scientific statement of the European Heart Rhythm Association (EHRA) and the European Association of Percutaneous Cardiovascular Interventions (EAPCI) of the ESC endorsed by the Heart Rhythm Society (HRS), the Asian Pacific Heart Rhythm Society (APHRS) and the Canadian Heart Rhythm Society (CHRS)
Jean-Claude Deharo and others
Up to one third of patients referred for transcatheter tricuspid valve intervention (TTVI) have a transvalvular pacemaker (PPM) or implantable cardioverter-defibrillator (ICD) lead in place. Both the electrophysiology and interventional cardiology communities have been alerted to the complexity of decision making in this ...
Left atrial intramyocardial fat at pulmonary vein reconnection sites during atrial fibrillation redo ablation
Federico Landra and others
EP Europace, Volume 27, Issue 2, February 2025, euaf038, https://doi.org/10.1093/europace/euaf038
Aims Electrical reconnections between pulmonary veins (PVs) and the left atrium (LA) are frequently responsible for atrial fibrillation (AF) recurrences after pulmonary vein isolation (PVI). Multidetector computed tomography (MDCT)-derived images can be post-processed to detect intramyocardial fat (inFAT) by signal ...
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