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S. Blazek, M. Roeder, C. Besler, J. Seeburger, T. Noack, F.W. Mohr, C. Luecke, M. Gutberlet, A. Linke, G. Schuler, P. Lurz, P1366
Acute and chronic remodeling after interventional edge-to-edge repair of mitral regurgitation using cardiac magnetic resonance imaging, European Heart Journal, Volume 38, Issue suppl_1, August 2017, ehx502.P1366, https://doi.org/10.1093/eurheartj/ehx502.P1366 - Share Icon Share
Extract
Objectives: Given the frailty of patients receiving interventional edge-to-edge repair of mitral regurgitation (MR) using the MitraClip-system, optimal patient selection is desired.
Background: Several haemodynamic and echocardiographic studies suggest acute benefits for LV function and cardiac index (CI) following reduction in LV preload using the MitraClip. From a physiological point of view, MR reduction results in an increase in LV afterload. The impact of this afterload increase on LV and RV performance acutely as well the potential of positive remodelling during follow-up (FU) remain unclear.
Previous echocardiographic studies are limited by the inability to truly quantify effective ventricular stroke volume (SV) and atrioventricular valvular function. Aim of this prospective study was to assess the acute and late changes in left ventricular (LV) and right ventricular (RV) function using cardiac magnetic resonance (CMR) imaging as the considered reference standard in this setting
Methods: 38 Patients with severe symptomatic MR and high surgical risk (mean Euroscore II of 11.0±6.6) underwent MitraClip-implantation and CMR imaging before (4±6 days), within 7±10 days and 196±23 days after the procedure.