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Figure 4. Averaged ( n = 10) principal component analysis (PCA) for phenanthridine (PN) prepared in Daphnia magna media, 0.01% acetone (ACT), and 0.01% acetonitrile (ACN) in comparison to their respective controls consisting of the D. magna media, 0.01%-ACT, and 0.01%-ACN, respectively. Statistical signi

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in Do co-solvents used in exposure studies equally perturb the metabolic profile of Daphnia magna?

Published: 17 April 2025

Figure 2. Averaged ( n = 10) principal component analysis (PCA) for Daphnia magna media control group and co-solvent exposure groups including acetone (ACT), acetonitrile (ACN), methanol (MeOH), and dimethyl sulfoxide (DMSO) at three different levels (0.01%, 0.05%, and 0.1% v/v). Statistical significance (

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Total number of statistically significant (p < 0.05) perturbed ... Get access

in Do co-solvents used in exposure studies equally perturb the metabolic profile of Daphnia magna?

Published: 17 April 2025

Figure 5. Total number of statistically significant ( p < 0.05) perturbed metabolites that were up- or downregulated relative to the controls in the following treatments: 0.01% acetone (ACT), 0.01% acetonitrile (ACN), phenanthridine (PN) prepared in Daphnia magna ( D. magna -PN), PN prepared in 0.01%-AC

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Do co-solvents used in exposure studies equally perturb the metabolic profile of Daphnia magna? Get access

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Overview of the two experiments that comprised the study. In part 1, exposu... Get access

in Do co-solvents used in exposure studies equally perturb the metabolic profile of Daphnia magna?

Published: 17 April 2025

Figure 1. Overview of the two experiments that comprised the study. In part 1, exposure treatments consisting of different co-solvents including acetone (ACT), acetonitrile (ACN), methanol (MeOH), and dimethyl sulfoxide (DMSO) applied at varying concentrations. In part 2, co-solvents that were found to be the

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(A) Number of perturbed metabolic pathways and (B) number of perturbed norm... Get access

in Do co-solvents used in exposure studies equally perturb the metabolic profile of Daphnia magna?

Published: 17 April 2025

Figure 3. (A) Number of perturbed metabolic pathways and (B) number of perturbed normalized metabolite concentrations (up- or downregulation relative to the control group) after exposing Daphnia magna to different co-solvents including acetone (ACT), acetonitrile (ACN), methanol (MeOH), and dimethyl sulfoxi

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in Effects of organic and inorganic contaminants and their mixtures on metabolic health and gene expression in developmentally exposed zebrafish

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Graphical Abstract Get access

Averaged (n = 10) principal component analysis (PCA) for phenanthr... Get access

Averaged (n = 10) principal component analysis (PCA) for Daphn... Get access

Total number of statistically significant (p < 0.05) perturbed ... Get access

Field application doses of fipronil and 2,4-D and toxic effects on non-target soil organisms: a microcosm-level approach Get access

Microplastic contamination is widespread across invertebrate taxa frequently consumed by terrestrial vertebrates

A Modelling Approach to Predict Population-level Impact of Silver (Ag) to Rainbow Trout (Oncorhynchus mykiss)

Do co-solvents used in exposure studies equally perturb the metabolic profile of Daphnia magna? Get access

Overview of the two experiments that comprised the study. In part 1, exposu... Get access

(A) Number of perturbed metabolic pathways and (B) number of perturbed norm... Get access

Mercury trophic transfer to a freshwater biosentinel: quantifying controlled bioaccumulation in larval dragonflies

Exposure to Cotton and Polyester Microfibers Leads to Different Fatty Acid Profiles and Chemical Contaminants (PBDE) Concentrations in Juvenile Rainbow Trout (Oncorhynchus mykiss) Get access

Bioaccumulation and Uptake Kinetics of Per- and Polyfluoroalkyl Substances in Pimephales promelas

Graphical abstract

Effects of organic and inorganic contaminants and their mixtures on metabolic health and gene expression in developmentally exposed zebrafish

Progress on New Approach Methods (NAMs) in Ecotoxicology Get access

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