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Journal Article
Clinical profile and outcomes among patients with cardiac implantable electronic device presenting as isolated pocket infection, pocket-related infective endocarditis, or lead-related infective endocarditis
Wojciech Jacheć and others
in
EP Europace
EP Europace, Volume 27, Issue 4, April 2025, euaf053, https://doi.org/10.1093/europace/euaf053
Published: 14 March 2025
...Wojciech Jacheć; Anna Polewczyk; Dorota Nowosielecka; Andrzej Kutarski Isolated pocket infection Pocket infection complicated by infective endocarditis Medical University of Silesia Katowice, Poland scientific BNW-1-115/K/3/K Corresponding author. Tel: +48600024074. E-mail address...
Journal Article
Perioperative management and inflammatory marker monitoring in a cardiac surgery patient treated with tocilizumab: a case report of successful surgical aortic valve replacement
Masashi Toyama and others
European Heart Journal - Case Reports, Volume 9, Issue 3, March 2025, ytaf085, https://doi.org/10.1093/ehjcr/ytaf085
Published: 24 February 2025
... cytokine crucial for wound healing and infection response. Tocilizumab (TCZ), a monoclonal antibody against IL-6 receptors acting as a disease-modifying anti-rheumatic drug (DMARD), is used to treat idiopathic multicentric Castleman disease (iMCD). Regarding perioperative management, the current guidelines...
Journal Article
EDITOR'S CHOICE
Low LDL cholesterol and risk of bacterial and viral infections: observational and Mendelian randomization studies
Marianne Benn and others
European Heart Journal Open, Volume 5, Issue 1, January 2025, oeaf009, https://doi.org/10.1093/ehjopen/oeaf009
Published: 03 February 2025
... associations of low plasma LDL cholesterol with risk of bacterial and viral infections in 119 805 individuals from the Copenhagen General Population Study/Copenhagen City Heart Study, 468 701 from the UK Biobank, and up to 376 773 from the FinnGen Research Project. Observationally, low LDL cholesterol...
Journal Article
Two-in-one procedure for transvenous lead extraction and leadless pacemaker reimplantation in pacemaker-dependent patients with device infection: streamlined patient flow
Baptiste Maille and others
in
EP Europace
EP Europace, Volume 26, Issue 7, July 2024, euae162, https://doi.org/10.1093/europace/euae162
Published: 20 July 2024
... the terms of the Creative Commons Attribution License ( https://creativecommons.org/licenses/by/4.0/ ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Leadless pacemaker Transvenous lead removal Device-related infection...
Journal Article
Chronic kidney disease and transvenous cardiac implantable electronic device infection—is there an impact on healthcare utilization, costs, disease progression, and mortality?
David J Wright and others
in
EP Europace
EP Europace, Volume 26, Issue 7, July 2024, euae169, https://doi.org/10.1093/europace/euae169
Published: 19 June 2024
.... Abstract Aims Cardiac implantable electronic device (CIED) infections are a burden to hospitals and costly for healthcare systems. Chronic kidney disease (CKD) increases the risk of CIED infections, but its differential impact on healthcare utilization, costs, and outcomes is not known. Methods...
Journal Article
Infectious mass debulking in lead-associated endocarditis with a percutaneous aspiration system
Roland Heck and others
in
EP Europace
EP Europace, Volume 26, Issue 6, June 2024, euae151, https://doi.org/10.1093/europace/euae151
Published: 04 June 2024
... via the Permissions link on the article page on our site—for further information please contact [email protected]. Abstract Aims Debulking of infective mass to reduce the burden if infective material is a fundamental principle in the surgical management of infection. The aim...
Journal Article
Cardiac implantable electronic devices and bloodstream infections: management and outcomes
Tardu Özkartal and others
European Heart Journal, Volume 45, Issue 14, 7 April 2024, Pages 1269–1277, https://doi.org/10.1093/eurheartj/ehae127
Published: 28 March 2024
...Tardu Özkartal; Andrea Demarchi; Giulio Conte; Damiano Pongan; Catherine Klersy; Maria Luce Caputo; Marco Bergonti; Enos Bernasconi; Valeria Gaia; Christopher B Granger; Angelo Auricchio 03 07 2023 18 01 2024 15 02 2024 Bloodstream infection was defined as the presence of blood cultures...
Journal Article
Persistent increase of cardiovascular and cerebrovascular events in COVID-19 patients: a 3-year population-based analysis
Allegra Battistoni and others
Cardiovascular Research, Volume 120, Issue 6, April 2024, Pages 623–629, https://doi.org/10.1093/cvr/cvae049
Published: 19 March 2024
...Allegra Battistoni; Massimo Volpe; Carmine Morisco; Gaetano Piccinocchi; Roberto Piccinocchi; Massimo Fini; Stefania Proietti; Stefano Bonassi; Bruno Trimarco Graphical Abstract Graphical Abstract SARS-COV-2 Atrial fibrillation Myocardial infarction Heart failure Stroke Viral infection...
Journal Article
ISG15 blocks cardiac glycolysis and ensures sufficient mitochondrial energy production during Coxsackievirus B3 infection
Clara Bredow and others
Cardiovascular Research, Volume 120, Issue 6, April 2024, Pages 644–657, https://doi.org/10.1093/cvr/cvae026
Published: 03 February 2024
...-embryonic cardiomyocytes, yielding >90% troponin-I-positive cells, has been described elsewhere. 19 We obtained about 7–9 embryos for both WT and ISG15−/− condition from each mother and sacrificed 1–2 animals for each experiment. Cardiomyocytes were infected with CVB3 at an MOI...
Journal Article
EDITOR'S CHOICE
PCSK9 genetic variants and risk of vascular and non-vascular diseases in Chinese and UK populations
Michael V Holmes and others
European Journal of Preventive Cardiology, Volume 31, Issue 8, June 2024, Pages 1015–1025, https://doi.org/10.1093/eurjpc/zwae009
Published: 10 January 2024
...]. We also replicated associations for a PCSK9 variant, reported in UK Biobank, with increased risks of acute upper respiratory tract infection (URTI) [pooled OR after meta-analysis of 1.87 (1.38–2.54); P = 5.4 × 10−5] and self-reported asthma [pooled OR of 1.17 (1.04–1.30...
Journal Article
Lead extraction today: a matter of time or a matter of way?
Igor Diemberger and Federico Migliore
in
EP Europace
EP Europace, Volume 25, Issue 11, November 2023, euad325, https://doi.org/10.1093/europace/euad325
Published: 31 October 2023
... of the lead extraction ‘tool box’ implying the having a variety of tools available increases the success and safety of the procedure. Moreover, despite the chosen approach, current outcomes of TLE clearly outweigh the risk of postponing the procedure, especially for patients with CIED infection. No funding...
Journal Article
Use of a taurolidine containing antimicrobial wash to reduce cardiac implantable electronic device infection
Stefan Borov and others
in
EP Europace
EP Europace, Volume 25, Issue 10, October 2023, euad306, https://doi.org/10.1093/europace/euad306
Published: 13 October 2023
... device (CIED) infection, was compared with a historical control of 3% hydrogen peroxide (H2O2) in a prospective observational study. Methods and results The device pocket was irrigated, and all hardware accessible within (leads, suture sleeves, pulse generator) was wiped...
Journal Article
Real-world evidence on the association between cardiac implantable electronic device infection and all-cause mortality
Md Shajedur Rahman Shawon and others
in
EP Europace
EP Europace, Volume 25, Issue 9, September 2023, euad274, https://doi.org/10.1093/europace/euad274
Published: 13 September 2023
...Md Shajedur Rahman Shawon; Oluwadamisola Temilade Sotade; Michelle Hill; Liesl Strachan; Gabrielle Challis; Sze-Yuan Ooi; Louisa R Jorm CIED infection All-cause mortality Pacemaker Pocket infection NHMRC 10.13039/501100000925 #APP11447430 Medtronic Australasia Pty Ltd Corresponding...
Journal Article
GUIDELINES
2023 ESC Guidelines for the management of endocarditis: Developed by the task force on the management of endocarditis of the European Society of Cardiology (ESC) Endorsed by the European Association for Cardio-Thoracic Surgery (EACTS) and the European Association of Nuclear Medicine (EANM)
Victoria Delgado and others
European Heart Journal, Volume 44, Issue 39, 14 October 2023, Pages 3948–4042, https://doi.org/10.1093/eurheartj/ehad193
Published: 25 August 2023
... Diagnosis Echocardiography Endocarditis Infection Nuclear imaging Positron emission tomography Prevention Prognosis Prosthetic heart valve Valve disease 1. Preamble 3953 2. Introduction 3955 2.1. What is new 3955 3. Prevention 3959 3.1. Rationale 3959 3.2. Populations at risk...
Journal Article
Cardiac implantable electronic device implantation and device-related infection
Vivek Modi and others
in
EP Europace
EP Europace, Volume 25, Issue 9, September 2023, euad208, https://doi.org/10.1093/europace/euad208
Published: 11 August 2023
... with device-related infection (DRI) from 2011 to 2018. Trends for coronary artery disease (P = 0.94) and end-stage renal disease (P = 0.88) were statistically insignificant while all other comorbidities showed significant interval increase (P < 0.001 for all others). CAD...
Journal Article
REducing INFectiOns thRough Cardiac device Envelope: insight from real world data. The REINFORCE project
Matteo Ziacchi and others
in
EP Europace
EP Europace, Volume 25, Issue 11, November 2023, euad224, https://doi.org/10.1093/europace/euad224
Published: 26 July 2023
... modification date and exit dates. We calculated for each patient the raw PADIT risk scores 11 and the relative risk of infection-related events for each score was estimated and reported as Odds Ratio, together with its 95% CI as a sensitivity analysis. To account for differences in baseline...
Journal Article
Long-term survival following transvenous lead extraction: unpicking differences according to sex
Vishal S Mehta and others
in
EP Europace
EP Europace, Volume 25, Issue 9, September 2023, euad214, https://doi.org/10.1093/europace/euad214
Published: 19 July 2023
...-morbidity burden (2.75 vs. 1.78, P < 0.001), and an infective indication for extraction (n = 287, 55.0% vs. n = 200, 64.1%, P = 0.012). Figure 1 Kaplan–Meier survival probability in patients stratified by sex. CI, confidence interval; HR, hazard ratio. Within...
Journal Article
Procedure, management, and outcome of subcutaneous implantable cardioverter–defibrillator extraction in clinical practice
Paolo De Filippo and others
in
EP Europace
EP Europace, Volume 25, Issue 6, June 2023, euad158, https://doi.org/10.1093/europace/euad158
Published: 23 June 2023
... to infection). The S-ICD system was successfully extracted in all patients, and no complications were reported; the median procedure duration was 40 (25th–75th percentile: 20–55) min. Simple manual traction was sufficient to remove the lead in 59 (84%) patients, in whom lead-dwelling time was shorter [20 (9–32...
Journal Article
Cost-effectiveness of an antibacterial envelope for infection prevention in patients undergoing cardiac resynchronization therapy reoperations in Denmark
Maria Hee Jung Park Frausing and others
in
EP Europace
EP Europace, Volume 25, Issue 6, June 2023, euad159, https://doi.org/10.1093/europace/euad159
Published: 22 June 2023
...Maria Hee Jung Park Frausing; Jens Brock Johansen; Daniela Afonso; Ole Dan Jørgensen; Thomas Olsen; Christian Gerdes; Mette Lundsby Johansen; Claudia Wolff; Stuart Mealing; Jens Cosedis Nielsen; Mads Brix Kronborg Cardiac resynchronization therapy Infection Cost-effectiveness analysis...
Journal Article
Myocarditis in a young male affected with monkeypox infection: a case report
Sergio Luengo Pérez and others
European Heart Journal - Case Reports, Volume 7, Issue 5, May 2023, ytad211, https://doi.org/10.1093/ehjcr/ytad211
Published: 25 April 2023
...Sergio Luengo Pérez; Julián Abdala Lizarraga; Esther Jaén Ferrer; Francisco Ridocci Soriano; Sadaf Raza; Mark Abela; Matthew Williams; Nikolaos Spinthakis; Nikesh Jathanna Learning points Monkeypox infection is generally self-limiting with low mortality. Scientific evidence suggests benign...