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Keywords: computational fluid dynamics
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Journal Article
CT-FFR by expanding coronary tree with Newton–Krylov–Schwarz method to solve the governing equations of CFD
Weifeng Guo and others
European Heart Journal - Imaging Methods and Practice, Volume 2, Issue 3, July 2024, qyae106, https://doi.org/10.1093/ehjimp/qyae106
Published: 24 October 2024
... and (B) the vessel level. computational fluid dynamics coronary CT angiography fractional flow reserve intermediate lesions Newton–Krylov–Schwarz algorithm Abstract Aims A new model of computational fluid dynamics (CFD)-based algorithm for coronary CT angiography (CCTA)-derived fractional flow...
Journal Article
EDITOR'S CHOICE
Can β-blockers prevent intracranial aneurysm rupture?: insights from Computational Fluid Dynamics analysis
Kornelia M Kliś and others
Cardiovascular Research, Volume 120, Issue 18, December 2024, Pages 2408–2419, https://doi.org/10.1093/cvr/cvae158
Published: 30 July 2024
... performed Computational Fluid Dynamics analysis of blood flow through the modelled structures. Blood was modelled as Newtonian fluid, using the incompressible transient solver. As the inlet boundary condition, we used the patient-specific Internal Carotid Artery blood velocity waves obtained with Doppler...
Journal Article
Mixing properties of coronary infusion catheters assessed by in vitro experiments and computational fluid dynamics
Annemiek de Vos and others
European Heart Journal - Digital Health, Volume 5, Issue 4, July 2024, Pages 491–501, https://doi.org/10.1093/ehjdh/ztae033
Published: 16 May 2024
... semi-quantitatively by temperature measurements in the bench model. Lastly, a quantitative assessment was performed by 3D computational fluid dynamics, where the standard deviation and entropy ratio of the temperature over the cross-section in the coronary artery model were calculated for both...
Journal Article
Benefit of icosapent ethyl on coronary physiology assessed by computed tomography angiography fractional flow reserve: EVAPORATE-FFRCT
Mark G Rabbat and others
European Heart Journal - Cardiovascular Imaging, Volume 24, Issue 7, July 2023, Pages 866–873, https://doi.org/10.1093/ehjci/jead063
Published: 22 April 2023
... plaque burden. No study to date has assessed the impact of IPE on coronary physiology. Fractional flow reserve (FFR) derived from coronary computed tomography angiography (CTA) data sets (FFRCT) applies computational fluid dynamics to calculate FFR values in epicardial coronary arteries. Our...
Journal Article
Rapid virtual fractional flow reserve using 3D computational fluid dynamics
Thomas Newman and others
European Heart Journal - Digital Health, Volume 4, Issue 4, August 2023, Pages 283–290, https://doi.org/10.1093/ehjdh/ztad028
Published: 21 April 2023
... recommended assessment to guide coronary interventions. Although the speed of vFFR computation has accelerated, techniques utilising full 3D computational fluid dynamics (CFD) solutions rather than simplified analytical solutions still require significant time to compute. Methods and results This study...
Journal Article
Validation of a novel numerical model to predict regionalized blood flow in the coronary arteries
Daniel J Taylor and others
European Heart Journal - Digital Health, Volume 4, Issue 2, March 2023, Pages 81–89, https://doi.org/10.1093/ehjdh/ztac077
Published: 03 January 2023
... a computational fluid dynamics (CFD) method for predicting flow that differentiates inlet, side branch, and outlet flows during angiography. In the current study, we evaluate a new method that regionalizes flow along the length of the artery. Methods and results Three-dimensional coronary anatomy...
Journal Article
An artificial intelligence-based platform for automatically estimating time-averaged wall shear stress in the ascending aorta
Lei Lv and others
European Heart Journal - Digital Health, Volume 3, Issue 4, December 2022, Pages 525–534, https://doi.org/10.1093/ehjdh/ztac058
Published: 14 October 2022
...Lei Lv; Haotian Li; Zonglv Wu; Weike Zeng; Ping Hua; Songran Yang Figure 2 The process of computational fluid dynamics analysis and time-averaged wall shear stress calculation. Shortly, we first labelled the mask of aorta, containing aortic root, aortic sinus, sinotubular junction, ascending...
Journal Article
Detailed behaviour of endothelial wall shear stress across coronary lesions from non-invasive imaging with coronary computed tomography angiography
Inge J van den Hoogen and others
European Heart Journal - Cardiovascular Imaging, Volume 23, Issue 12, December 2022, Pages 1708–1716, https://doi.org/10.1093/ehjci/jeac095
Published: 25 May 2022
... atherosclerosis. All patients were symptomatic with prevalent cardiac risk factors and medication use. In particular, a high prevalence of hypertension (74%) and dyslipidaemia (74%) was observed. atherosclerosis coronary artery disease endothelial wall shear stress computational fluid dynamics coronary...
Journal Article
Assessing the methodology used to study the ascending aorta haemodynamics in bicuspid aortic valve
Joy Edlin and others
European Heart Journal - Digital Health, Volume 2, Issue 2, June 2021, Pages 271–278, https://doi.org/10.1093/ehjdh/ztab022
Published: 11 June 2021
... with diseased and healthy BAV and TAV. 27 In our latest endeavour, we sought to investigate the haemodynamic behaviour of blood flow in the ascending aorta before and after isolated tissue aortic valve replacement in patients with stenosed BAV and TAV. Computational fluid dynamics can analyse...
Journal Article
Interpretation of coronary steal syndrome and haemodynamic changes after surgical closure of coronary fistula using Doppler wire and computational fluid dynamics analysis: a case report
Kwan Yong Lee and others
European Heart Journal - Case Reports, Volume 5, Issue 4, April 2021, ytab069, https://doi.org/10.1093/ehjcr/ytab069
Published: 24 April 2021
...Kwan Yong Lee; Kiyuk Chang; Joo Myung Lee; Sang-Wook Lee; Joseph Moutiris; Erica Tirr; Doralisa Morrone; Alexander Tindale; Anthony Paulo Sunjaya Figure 3 Wall shear stress and oscillatory shear index maps by computational fluid dynamics of the coronary fistula. (A) High wall shear...
Journal Article
High spatial endothelial shear stress gradient independently predicts site of acute coronary plaque rupture and erosion
Vikas Thondapu and others
Cardiovascular Research, Volume 117, Issue 8, 1 July 2021, Pages 1974–1985, https://doi.org/10.1093/cvr/cvaa251
Published: 24 August 2020
... Proximal shoulder 12 (63%) 4 (22%) 0.01 Distal shoulder 7 (37%) 14 (78%) CFD, computational fluid dynamics; HDL, high density lipoprotein; LAD, left anterior descending artery; LDL, low density lipoprotein; LCx, left circumflex artery; NSTE-ACS, non-ST-elevation acute coronary syndrome; RCA...
Journal Article
A novel method for measuring absolute coronary blood flow and microvascular resistance in patients with ischaemic heart disease
Paul D Morris and others
Cardiovascular Research, Volume 117, Issue 6, 1 June 2021, Pages 1567–1577, https://doi.org/10.1093/cvr/cvaa220
Published: 14 July 2020
... a novel method that predicts absolute coronary blood flow and microvascular resistance (MVR) in the catheter laboratory. Methods and results A computational fluid dynamics (CFD) model was used to predict absolute coronary flow (QCFD) and coronary MVR using data from routine invasive...
Journal Article
Referral of patients for fractional flow reserve using quantitative flow ratio
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Jeff M Smit and others
European Heart Journal - Cardiovascular Imaging, Volume 20, Issue 11, November 2019, Pages 1231–1238, https://doi.org/10.1093/ehjci/jey187
Published: 11 December 2018
... coronary angiography and computational fluid dynamics, obviating the need for a pressure-wire and hyperaemia induction. QFR might be used to guide patient selection for FFR and subsequent percutaneous coronary intervention (PCI) referral in hospitals not capable to perform FFR and PCI. We aimed...
Journal Article
Activities at Thoracic Aortic Research Center, IRCCS Policlinico San Donato
Santi Trimarchi and others
European Heart Journal Supplements, Volume 18, Issue suppl_E, April 2016, Pages E57–E63, https://doi.org/10.1093/eurheartj/suw015
Published: 29 April 2016
... is structured, for in silico analysis utilizing computational fluid dynamics, and in vitro studies using also 3D printed aortic models. With the role of principal investigator or co-investigator, TARC at PSD has been participating in other several projects, including the International Registry...
Journal Article
Coronary plaque quantification and fractional flow reserve by coronary computed tomography angiography identify ischaemia-causing lesions
Sara Gaur and others
European Heart Journal, Volume 37, Issue 15, 14 April 2016, Pages 1220–1227, https://doi.org/10.1093/eurheartj/ehv690
Published: 12 January 2016
... assessment and FFRCT provide improved discrimination of ischaemia compared with stenosis assessment alone. Coronary plaque Computed tomography angiography Computational fluid dynamics Fractional flow reserve Ischaemia See page 1228 for the editorial comment on this article (doi:10.1093...
Journal Article
Impact of competitive flow on wall shear stress in coronary surgery: computational fluid dynamics of a LIMA–LAD model
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Håvard Nordgaard and others
Cardiovascular Research, Volume 88, Issue 3, 1 December 2010, Pages 512–519, https://doi.org/10.1093/cvr/cvq210
Published: 24 June 2010
... atherosclerosis and intimal hyperplasia. The aim was to investigate the impact of competitive flow on WSS in mammary artery bypass grafts. Methods and results Using computational fluid dynamics, WSS was calculated in a left internal mammary artery (LIMA) graft to the left anterior descending artery in a three...
Journal Article
Utility of the Proximal Jet Width in the Assessment of Regurgitant and Stenotic Orifices — Effect of Low Velocity Filter and Comparison to Actual Vena Contracta Width: an In Vitro and Numerical Study
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C.G. Degroff and others
European Journal of Echocardiography, Volume 1, Issue 1, March 2000, Pages 42–54, https://doi.org/10.1053/euje.1999.0005
Published: 01 March 2000
.... Methods: Computational fluid dynamic software was used to create models of round orifices (0·785, 1·13, 1·76, 3·14 cm 2 ) at set flow rates (0·37–25 l/min). In vitro experiments were performed with round orifices (0.2, 0·95 and 1·76 cm 2 ) with set flow rates (1·8–3·6 l/min...
Chapter
CT-based fractional flow reserve
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Domenico Mastrodicasa
Published: 01 November 2022
... of computational fluid dynamics to the patient-specific anatomical three-dimensional model of the coronary tree obtained with the CCTA. As a result, CT-FFR can be computed and displayed at any point along the coronary vessels. This chapter includes practical information to help the physician using CT-FFR...