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Nuclear techniques have contributed to the diagnosis and management of patients with coronary artery disease (CAD) over the past 50 years. The various nuclear modalities available to the clinician and patient keep evolving with tremendous advances in therapeutics occurring in the cardiovascular space. This evolution has followed a steady pattern of individual observations in patients or small cohorts to collection of large databases by single and multicentre investigators. These registries over the years have informed us about the value of risk stratification of patients presenting for evaluation of CAD, patients with established CAD, patients being considered for revascularization to guide therapies, patients post-revascularization to assess progression of disease or completeness of revascularization, and finally assessing myocardial scaring and hibernation, to name but a few contributions of the field.
Although CAD remains the bread and butter of daily nuclear cardiology practice, many new windows have opened over the past few years, making nuclear cardiology an indispensable tool in the diagnosis and management of patients with heart failure (ischaemic and non-ischaemic), amyloid heart disease, endocarditis, myocarditis, and cardiac sarcoidosis.
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