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Antonio V Sterpetti, Monica Campagnol, Raimondo Gabriele, Women with acute and chronic myocardial ischaemia have worse early results after PTCA and CABG, but better 1-year results, European Heart Journal - Quality of Care and Clinical Outcomes, Volume 10, Issue 8, December 2024, Page 763, https://doi.org/10.1093/ehjqcco/qcae046
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We read with much interest the paper by Cenko et al.1 The authors analysed data from the ISACS-Archives registry including 22 087 patients with myocardial infarction from six high-income countries and six middle-income countries in Europe. They found higher 30-day mortality rates for women; this disparity was more evident in middle-income countries. We analysed the reports of the Italian National Agency AGENAS2 concerning clinical outcomes of patients admitted for acute and chronic symptoms of myocardial ischaemia in Italy during the years 2021 and 2022; overall, 30-day mortality was higher for women. During the analysed period, 214 529 patients were admitted to hospital for acute/chronic myocardial ischaemia: 30-day mortality for patients with acute myocardial ischaemia was 7.7% [95% confidence interval (CI) 7.0–8.2]; 30-day mortality for patients with ST-segment elevation myocardial infarction (STEMI) was 9.2% (95% CI 8.6–9.8) (Table 1).
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The AGENAS includes a detailed analysis of a randomly selected group of 46 805 patients, admitted for acute myocardial ischaemia who had percutaneous transluminal coronary angioplasty (PTCA): the 30-day adjusted mortality rate for patients with STEMI was higher in females [adjusted odds ratio (OR) 1.04; 95% CI 0.95–1.14 P = 0.06].