https://orcid.org/0000-0002-0039-5677
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Elisa Bass, John Asher Jenkins, Juan M Farina, Andrew Saleeb, Staci E Beamer, Dawn E Jaroszewski, Samine Ravanbakhsh, Cecilia Benz, Pedro Reck dos Santos, Jonathan D’Cunha, The role of computed tomography and endoscopy in caustic esophageal injury in adults: a systematic review, Diseases of the Esophagus, Volume 38, Issue 3, June 2025, doaf037, https://doi.org/10.1093/dote/doaf037
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Summary
Caustic esophageal injury can cause severe morbidity and mortality. Despite the need for emergent treatment, individual experience in diagnosis and management can be limited. Computed tomography (CT) has emerged as a promising non-invasive modality for assessing injury severity, but the clinical utility of both CT and endoscopy should be investigated. A systematic review was conducted following PRISMA guidelines. A comprehensive search of the PubMed database identified relevant articles published from January 1, 2000 to December 31, 2023. Inclusion criteria encompassed studies investigating the use of CT and/or endoscopy in diagnosing and managing caustic esophageal injury. Twelve articles were selected from a pool of 931 studies. Findings suggested that CT was superior in diagnostic capability to endoscopy in high-grade injury and stricture formation, but less so for low grade injuries. Diagnostic algorithms incorporating imaging with laboratory studies have emerged in the literature, which are promising pending additional validation. CT can serve as a valuable, non-invasive tool in the initial evaluation of caustic esophageal injury and is postulated to accurately predict both the need for emergent surgery and the risk of stricture formation. However, CT should not replace but rather complement the use of endoscopy to comprehensively evaluate these potentially highly morbid situations.
