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High-Impact Research from DNA Research

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Explore a collection of the most read and most cited articles making an impact in DNA Research published within the past two years. This collection will be continuously updated with the journal's leading articles so be sure to revisit periodically to see what is being read and cited.

Also discover the articles being discussed the most on digital media by exploring this Altmetric report pulling the most discussed articles from the past year.

Most cited

Telomere-to-telomere genome assembly of matsutake (Tricholoma matsutake)
Hiroyuki Kurokochi and others
DNA Research, Volume 30, Issue 3, June 2023, dsad006, https://doi.org/10.1093/dnares/dsad006
Here, we report the first telomere-to-telomere genome assembly of matsutake ( Tricholoma matsutake ), which consists of 13 sequences (spanning 161.0 Mb) and a 76 kb circular mitochondrial genome. All the 13 sequences were supported with telomeric repeats at the ends. GC-rich regions are located at the middle of the ...
Genome assembly of the pioneer species Plantago major L. (Plantaginaceae) provides insight into its global distribution and adaptation to metal-contaminated soil
Shanwu Lyu and others
DNA Research, Volume 30, Issue 4, August 2023, dsad013, https://doi.org/10.1093/dnares/dsad013
Plantago is a major genus belonging to the Plantaginaceae family and is used in herbal medicine, functional food, and pastures. Several Plantago species are also characterized by their global distribution, but the mechanism underpinning this is not known. Here, we present a high-quality, chromosome-level genome assembly of ...
Telomere-to-telomere genome assembly of an allotetraploid pernicious weed, Echinochloa phyllopogon
Mitsuhiko P Sato and others
DNA Research, Volume 30, Issue 5, October 2023, dsad023, https://doi.org/10.1093/dnares/dsad023
Echinochloa phyllopogon is an allotetraploid pernicious weed species found in rice fields worldwide that often exhibit resistance to multiple herbicides. An accurate genome sequence is essential to comprehensively understand the genetic basis underlying the traits of this species. Here, the telomere-to-telomere genome ...
Assessment of metagenomic workflows using a newly constructed human gut microbiome mock community
Hiroshi Mori and others
DNA Research, Volume 30, Issue 3, June 2023, dsad010, https://doi.org/10.1093/dnares/dsad010
To quantify the biases introduced during human gut microbiome studies, analyzing an artificial mock community as the reference microbiome is indispensable. However, there are still limited resources for a mock community which well represents the human gut microbiome. Here, we constructed a novel mock community comprising ...
Self-grafting-induced epigenetic changes leading to drought stress tolerance in tomato plants
Maria Isabel Fuentes-Merlos and others
DNA Research, Volume 30, Issue 4, August 2023, dsad016, https://doi.org/10.1093/dnares/dsad016
Grafting is widely used as a method to increase stress tolerance in good fruiting lines of Solanaceae plants. However, little is known about how grafting, affects epigenetic modifications and leads to stress tolerance, especially within the same line. Here, we studied the effects of self-grafting in tomato plants on ...
Chromosome-level genome assembly of an endangered plant Prunus mongolica using PacBio and Hi-C technologies
Qiang Zhu and others
DNA Research, Volume 30, Issue 4, August 2023, dsad012, https://doi.org/10.1093/dnares/dsad012
Prunus mongolica is an ecologically and economically important xerophytic tree native to Northwest China. Here, we report a high-quality, chromosome-level P. mongolica genome assembly integrating PacBio high-fidelity sequencing and Hi-C technology. The assembled genome was 233.17 Mb in size, with 98.89% assigned to eight ...
Detection of tandem repeats in the Capsicum annuum genome
Valentina Rudenko and Eugene Korotkov
DNA Research, Volume 30, Issue 3, June 2023, dsad007, https://doi.org/10.1093/dnares/dsad007
In this study, we modified the multiple alignment method based on the generation of random position weight matrices (RPWMs) and used it to search for tandem repeats (TRs) in the Capsicum annuum genome. The application of the modified (m)RPWM method, which considers the correlation of adjusting nucleotides, resulted in the ...
Genome sequence and salinity adaptation of the desert shrub Nitraria sibirica (Nitrariaceae, Sapindales)
Xiaohui Ma and others
DNA Research, Volume 30, Issue 3, June 2023, dsad011, https://doi.org/10.1093/dnares/dsad011
The genetic bases of halophytes for salinity tolerance are crucial for genetically breeding salt-tolerant crops. All natural Nitrariaceae species that exclusively occur in arid environments are highly tolerant to salt stress, but the underlying genomic bases to this adaptation remain unknown. Here we present a ...
Assessing genetic diversity and geographical differentiation in a global collection of wild soybean (Glycine soja Sieb. et Zucc.) and assigning a mini-core collection
Feng Li and others
DNA Research, Volume 31, Issue 2, April 2024, dsae009, https://doi.org/10.1093/dnares/dsae009
Wild soybean ( Glycine soja ), the ancestor of the cultivated soybean ( G. max ), is a crucial resource for capturing the genetic diversity of soybean species. In this study, we used a set of 78 genome-wide microsatellite markers to analyse the genetic diversity and geographic differentiation patterns in a global ...
ZSCAN4-binding motif—TGCACAC is conserved and enriched in CA/TG microsatellites in both mouse and human genomes
Tomohiko Akiyama and others
DNA Research, Volume 31, Issue 1, February 2024, dsad029, https://doi.org/10.1093/dnares/dsad029
The Zinc finger and SCAN domain containing 4 (ZSCAN4) protein, expressed transiently in pluripotent stem cells, gametes, and early embryos, extends telomeres, enhances genome stability, and improves karyotypes in mouse embryonic stem (mES) cells. To gain insights into the mechanism of ZSCAN4 function, we identified ...

Most read

Research Article
Chromosome-level genome assembly of Pontederia cordata L. provides insights into its rapid adaptation and variation of flower colours
Jia-Le Wang and others
DNA Research, Volume 32, Issue 2, April 2025, dsaf002, https://doi.org/10.1093/dnares/dsaf002
Pontederia cordata L. is an aquatic ornamental plant native to the Americas but has been widely distributed in South Asia, Australia, and Europe. The genetic mechanisms behind its rapid adaptation and spread have not yet been well understood. To understand the mechanisms for its rapid adaptation, this study assembled the ...
Research Article
Genomic variation across distribution of Micro-Tom, a model cultivar of tomato (Solanum lycopersicum)
Hideki Nagasaki and others
DNA Research, Volume 31, Issue 5, October 2024, dsae016, https://doi.org/10.1093/dnares/dsae016
Micro-Tom is a cultivar of tomato ( Solanum lycopersicum ), which is known as a major crop and model plant in Solanaceae. Micro-Tom has phenotypic traits such as dwarfism, and substantial EMS-mutagenized lines have been reported. After Micro-Tom was generated in Florida, USA, it was distributed to research institutes ...
Research Article
GINGER: an integrated method for high-accuracy prediction of gene structure in higher eukaryotes at the gene and exon level
Takeaki Taniguchi and others
DNA Research, Volume 30, Issue 4, August 2023, dsad017, https://doi.org/10.1093/dnares/dsad017
The prediction of gene structure within the genome sequence is the starting point of genome analysis, and its accuracy has a significant impact on the quality of subsequent analyses. Gene structure prediction is roughly divided into RNA-Seq-based methods, ab initio -based methods, homology-based methods, and the ...
Research Article
Identification of a candidate sex determination region and sex-specific molecular markers based on whole-genome re‑sequencing in the sea star Asterias amurensis
Yanlin Wang and others
DNA Research, Volume 32, Issue 1, February 2025, dsaf003, https://doi.org/10.1093/dnares/dsaf003
Sex determination systems are diverse in echinoderms, however, our understanding is still very limited in this research field, especially for Asteroidea species. The northern Pacific seastar, Asterias amurensis , has attracted widespread concern due to its population outbreaks and high-risk invasions. Using whole-genome ...
Research Article
Comparative transcriptome and mutation analyses of the pancreatic islets of a rat model of obese type 2 diabetes identifies a frequently distributed nonsense mutation in the lipocalin 2 gene
Norihide Yokoi and others
DNA Research, Volume 32, Issue 2, April 2025, dsaf004, https://doi.org/10.1093/dnares/dsaf004
Type 2 diabetes (T2D) is a multifactorial disease caused by insulin resistance and impaired insulin secretion from pancreatic β-cells, but the precise mechanisms remain to be elucidated. To identify primary genetic factors of T2D in a rat model, we performed comparative transcriptome and mutation analyses of the pancreatic ...
Research Article
Genome-resolved analysis of Serratia marcescens strain SMTT infers niche specialization as a hydrocarbon-degrader
Amanda C Ramdass and Sephra N Rampersad
DNA Research, Volume 32, Issue 1, February 2025, dsaf001, https://doi.org/10.1093/dnares/dsaf001
Bacteria that are chronically exposed to high levels of pollutants demonstrate genomic and corresponding metabolic diversity that complement their strategies for adaptation to hydrocarbon-rich environments. Whole genome sequencing was carried out to infer functional traits of Serratia marcescens strain SMTT recovered from ...
Research Article
Genome assembly of the pioneer species Plantago major L. (Plantaginaceae) provides insight into its global distribution and adaptation to metal-contaminated soil
Shanwu Lyu and others
DNA Research, Volume 30, Issue 4, August 2023, dsad013, https://doi.org/10.1093/dnares/dsad013
Plantago is a major genus belonging to the Plantaginaceae family and is used in herbal medicine, functional food, and pastures. Several Plantago species are also characterized by their global distribution, but the mechanism underpinning this is not known. Here, we present a high-quality, chromosome-level genome assembly of ...
Research Article
Near-complete telomere-to-telomere de novo genome assembly in Egyptian clover (Trifolium alexandrinum)
Mitsuhiko P Sato and others
DNA Research, Volume 32, Issue 1, February 2025, dsae036, https://doi.org/10.1093/dnares/dsae036
Egyptian clover ( Trifolium alexandrinum L.), also known as berseem clover, is an important forage crop to semi-arid conditions that was domesticated in ancient Egypt in 5,5000 BCE and introduced and well adapted to numerous countries including India, Pakistan, Turkey, and Mediterranean region. Despite its agricultural ...
Research Article
Pan-lineage Mycobacterium tuberculosis reference genome for enhanced molecular diagnosis
Kunhyung Bahk and others
DNA Research, Volume 31, Issue 4, August 2024, dsae023, https://doi.org/10.1093/dnares/dsae023
In Mycobacterium tuberculosis (MTB) control, whole genome sequencing-based molecular drug susceptibility testing (molDST-WGS) has emerged as a pivotal tool. However, the current reliance on a single-strain reference limits molDST-WGS’s true potential. To address this, we introduce a new pan-lineage reference genome, ...
Research Article
Metagenomic Thermometer
Masaomi Kurokawa and others
DNA Research, Volume 30, Issue 6, December 2023, dsad024, https://doi.org/10.1093/dnares/dsad024
Various microorganisms exist in environments, and each of them has its optimal growth temperature (OGT). The relationship between genomic information and OGT of each species has long been studied, and one such study revealed that OGT of prokaryotes can be accurately predicted based on the fraction of seven amino acids ...
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