1-20 of 44894
Journal Article
Quality Control Measurements Yield Similar Variation Below and Above Limit of Quantification for High-Sensitivity Cardiac Troponin I Assays Get access
Clinical Chemistry, hvaf057, https://doi.org/10.1093/clinchem/hvaf057
Published: 02 May 2025
Journal Article
Red Blood Cell-Bound Cell-Free DNA Is an Insensitive Marker for Diagnosis of Bacterial Infections Get access
Clinical Chemistry, hvaf053, https://doi.org/10.1093/clinchem/hvaf053
Published: 02 May 2025
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Within-subject BV of erythrocyte zinc protoporphyrin in participants with E...
Published: 02 May 2025
Fig. 4.
Within-subject BV of erythrocyte zinc protoporphyrin in participants with EPP and in healthy subjects. The figure displays median estimated personal within-subject BV (represented by squares for females and triangles for males) accompanied by their respective 95% credible intervals (depicted by hori
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Same lot of commercial QC measured between September 2022 through to Februa... Get access
Published: 02 May 2025
Fig. 1.
Same lot of commercial QC measured between September 2022 through to February 2025 on 10 Abbott ARICHTECT analyzers (n = 9589 results with overall mean = 3.0 ng/L; pooled SD = 0.9 with range of SD: 0.4 to 1.3), 1 Ortho Vitros XT 7600 analyzer (n = 1407 results with overall mean = 4.68 ng/L; SD = 0.9
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Within-subject biological variation of erythrocyte metal-free protoporphyri...
Published: 02 May 2025
Fig. 3.
Within-subject biological variation of erythrocyte metal-free protoporphyrin in participants with EPP. The figure displays median estimated personal within-subject BV (represented by squares for females and triangles for males) accompanied by their respective 95% credible intervals (depicted by hori
Journal Article
Biological Variation of Erythrocyte Total, Metal-Free, and Zinc Protoporphyrin IX in Patients with Erythropoietic Protoporphyria and Healthy Subjects: Implications for Clinical Interpretation and Monitoring
Clinical Chemistry, hvaf055, https://doi.org/10.1093/clinchem/hvaf055
Published: 02 May 2025
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Comparison of threshold cycle values for RBC-bound and plasma mitochondrial... Get access
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Red Blood Cell-Bound Cell-Free DNA Is an Insensitive Marker for Diagnosis of Bacterial Infections
Published: 02 May 2025
Fig. 1.
Comparison of threshold cycle values for RBC-bound and plasma mitochondrial cfDNA in patients with and without bloodstream infection and tuberculosis. Mitochondrial ND1 Ct values are plotted for RBC and plasma samples in patients with bloodstream infection (BSI) and no BSI (A) and in patient with
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Individual mean values (represented by squares for females and triangles fo...
Published: 02 May 2025
Fig. 1.
Individual mean values (represented by squares for females and triangles for males) and range (depicted by horizontal bars) of erythrocyte metal-free protoporphyrin in participants with EPP.
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Individual mean values (represented by squares for females and triangles fo...
Published: 02 May 2025
Fig. 2.
Individual mean values (represented by squares for females and triangles for males) and range (depicted by horizontal bars) of erythrocyte zinc protoporphyrin in participants with EPP (solid bars) and in healthy subjects (dashed bars).
Journal Article
Utilizing the Stability of Individual Homeostatic Setpoints over Time - A Step Forward on the Path to Personalized Laboratory Medicine Get access
Clinical Chemistry, hvaf022, https://doi.org/10.1093/clinchem/hvaf022
Published: 29 April 2025
Journal Article
A Professional Skeptic Get access
Clinical Chemistry, hvaf049, https://doi.org/10.1093/clinchem/hvaf049
Published: 28 April 2025
Journal Article
The Utility of the Immunoglobulin A Flag Used in Celiac Disease Serology Testing on a Particle-Based Multianalyte Technology Platform Get access
Clinical Chemistry, hvaf047, https://doi.org/10.1093/clinchem/hvaf047
Published: 25 April 2025
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Top flowchart is of CeD serology cascade. Numbers and percentages of tested... Get access
Published: 25 April 2025
Fig. 1.
Top flowchart is of CeD serology cascade. Numbers and percentages of tested patients grouped by TTG-IgA result ranges (FLU) are shown (arms A-D). Dotted boxes (DGP-IgA) indicate nonreportable results. Numbers/percentages of patients with elevated (≥5 FLU) within each arm are also shown on the graph.
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Accuracy assessment across sites. (A), Summary of assay performance measure... Get access
Published: 24 April 2025
Fig. 2.
Accuracy assessment across sites. (A), Summary of assay performance measured by recall, precision, and F1 score; (B), Summary of false-positive results across laboratories; (C), False-positive microbes reported among 16 samples; (D), The top 15 false-positive microorganisms with the highest occurren
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Repeatability assessment across laboratories. (A), Repeatability in the det... Get access
Published: 24 April 2025
Fig. 3.
Repeatability assessment across laboratories. (A), Repeatability in the detection of various microorganisms across 3 replicate samples by 130 laboratories; (B), Repeatability of microbial RPM values across various microorganisms in triplicate samples. *** P < 0.001 by Kruskal–Wallis tests; (C),
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The performance of metagenomic cfDNA sequencing in distinguishing genetical... Get access
Published: 24 April 2025
Fig. 4.
The performance of metagenomic cfDNA sequencing in distinguishing genetically similar microorganisms. Scatter plots show the RPM value of each microbe reported by laboratories in (A) sample S4 (2-fold change of theoretical ratio 0.17–0.67), (B) S5 (2-fold change of theoretical ratio 0.50–2.00), and
Journal Article
EDITOR'S CHOICE
MIQE 2.0: Revision of the Minimum Information for Publication of Quantitative Real-Time PCR Experiments Guidelines
Clinical Chemistry, hvaf043, https://doi.org/10.1093/clinchem/hvaf043
Published: 24 April 2025
Journal Article
A Comprehensive Assessment of Metagenomic cfDNA Sequencing for Microbe Detection Get access
Clinical Chemistry, hvaf044, https://doi.org/10.1093/clinchem/hvaf044
Published: 24 April 2025
Journal Article
The Need for Better Validation: Evaluating Aptamer and Proximity Extension Assays for Large-Scale Clinical Proteomics Studies Get access
Clinical Chemistry, hvaf046, https://doi.org/10.1093/clinchem/hvaf046
Published: 24 April 2025
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The multicenter quality assessment study design. In this study, a total of ... Get access
Published: 24 April 2025
Fig. 1.
The multicenter quality assessment study design. In this study, a total of 18 reference samples were designed and distributed to 130 laboratories. Each laboratory conducted detection using their routine metagenomic cfDNA sequencing procedures and submitted their results to the National Center for Cl
