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James G Carlucci, Thomas Huntington, Karl-Günter Technau, Marcel Yotebieng, Valériane Leroy, Kim Anderson, Madeleine Amorissani-Folquet, Kara Wools-Kaloustian, Andrew Edmonds, on behalf of the International epidemiology Databases to Evaluate AIDS Consortium, High Prevalence of Unconfirmed Positive HIV Polymerase Chain Reaction Test Results Among African Infants With HIV Exposure in the International Epidemiology Databases to Evaluate AIDS Consortium, Clinical Infectious Diseases, Volume 79, Issue 6, 15 December 2024, Pages 1475–1478, https://doi.org/10.1093/cid/ciae251
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Abstract
In a large, multiregional cohort of African infants with human immunodeficiency virus (HIV) exposure, 44% of those with a positive HIV polymerase chain reaction test lacked a confirmatory positive test. Efforts are needed to ensure high-fidelity implementation of HIV testing algorithms so that all positive results are confirmed.