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Allan R. Tunkel, Gary P. Wormser, Emerging Neurological Infections Edited by Christopher Power and Richard T. Johnson Boca Raton, FL: Taylor & Francis Group, 2005. 505 pp., illustrated. $199.95 (cloth), Clinical Infectious Diseases, Volume 42, Issue 2, 15 January 2006, Page 310, https://doi.org/10.1086/499058
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CNS infections are often devastating in their clinical presentation. Although significant advances have been made in molecular tools and neuroimaging techniques for diagnosis, as well as in anti-infective therapy, these diseases may still be difficult to diagnose and treat. Furthermore, CNS infections present unique dilemmas because of limitations in host defense mechanisms, the inability of some antimicrobial agents to penetrate the blood-brain barrier, the emergence of antimicrobial resistance, and the lack of effective therapies against some specific neuropathogens. Recent or remote infections with specific agents may also be associated with development of acute or chronic neurological diseases; identifying these associations may lead to important therapeutic and/or preventive strategies for these disorders.
The editors of this book have invited a group of internationally recognized experts to review the current state of information on these important neuropathogens, with specific emphasis on the epidemiology and spread of these agents, the factors that influence neurovirulence, and approaches to management of infection. When appropriate, the authors address these infections with respect to demographic characteristics, human behavior, technology and industry, international travel, microbial adaptation, and potential breakdowns of public health priorities as a result of poverty or social inequality.
