Volume 47, Issue 4, 1 April 2022

Malignant acanthosis nigricans has similar pathological manifestations with other diseases that have extensive oral papillary hyperplasia. However, this can make it difficult to distinguish between the other diseases based on lesions alone. To aid in the early detection of underlying malignant diseases, we summarize the clinical features of these diseases, and discuss the management of malignant acanthosis nigricans.

A review summarizing the role of thalidomide for dermatologists. The review provides case examples, explains the licensed and unlicensed doses of the medication for various conditions and the adverse effects to be aware of. Summary tables are also created for clinicians to glance through the salient points of the review.

Using six readability instruments, this study assessed the readability of the British Association of Dermatologists’ (BAD) patient information leaflets (PILs). The readability measures ascertained that most PILs provided by the BAD are written at a level that may not be comprehensible to a proportion of patients. We compare these findings to the literature and highlight methods for the BAD Clinical Standards Unit to improve readability for future PILs.

This systematic review and meta‐analysis demonstrates that patients with vitiligo do not have a significantly increased risk of skin cancer after ultraviolet phototherapy compared with those not receiving phototherapy.

Nonuraemic calciphylaxis is more common than previously reported, and was primarily seen in obese postmenopausal women. Undiagnosed primary hyperparathyroidism might be an overlooked risk factor and lupus anticoagulant was commonly present in nonuraemic and uraemic calciphylaxis patients. Histopathologically, extravascular calcification is more common in patients with nonuraemic calciphylaxis.

During isotretinoin treatment, special attention is required to detect any symptom or change in mental health. Our pilot, national, multicentre, prospective study assessed the acceptability of the Adolescent Depression Rating Scale for monitoring symptoms among adolescents before and during isotretinoin treatment in dermatology real‐life practice.

We present otological complications in the rare inversa subtype of recessive dystrophic epidermolysis bullosa, as well as experience with bone anchored hearing aids in this subgroup.

Recent evidence has suggested that oral antihistamines could have a beneficial role in atopic dermatitis (AD) due to their anti‐inflammatory action. The observations in the present study indicate that fexofenadine treatment can lead to significant lowering of levels of serum interleukin‐31, the major cytokine mediating itch, in patients with AD.

Two male patients living in conditions of vulnerability were affected by myiasis. Both were treated by ivermectin, debridement, antibiotic therapy and preventive care guidance. There is a need to implement care for prevention and attention to the general health of those patients affected by oral myiasis, as the lack of this is often a clear sign of neglect.

Sequential chemical peel therapy with salicylic acid and glycolic acid can be an effectual and prudent treatment option for difficult to treat cases of cutaneous amyloidosis.