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M. Lam, A. N. Patel, I. H. Leach, Nodule on the upper arm, Clinical and Experimental Dermatology, Volume 39, Issue 7, 1 October 2014, Pages 844–846, https://doi.org/10.1111/ced.12399
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Extract
Conflict of Interest: the authors declare that they have no conflicts of interest.
Clinical findings
A 2‐year‐old boy presented with a 3‐month history of a small lesion on his left upper arm. The boy's mother had noticed the lesion while she was applying emollients to the child's skin. The child was systemically well. He had been delivered at term without any complications. He had no developmental problems, and was up to date with his National Health Service vaccination schedule, including vaccinations with boosters against polio (at the ages of 2, 3 and 4 months) and measles, mumps and rubella (aged 13 months), diphtheria, tetanus, and pertussis. On physical examination, a small, solitary, symmetrical, mobile firm, subcutaneous grey papule, 5 mm in size, were seen on the left upper arm. The lesion was excised under general anaesthesia.
Histopathological findings
On histological examination of the lesion (Fig. 1a,b), a well circumscribed nodule was seen in the subcutis, comprising a necrobiotic granuloma with a central area of mainly amorphous eosinophilic material surrounded by palisading histiocytes and some plasma cells. Many of the histiocytes had slightly bluish granular cytoplasm. Stains for microorganisms (including diastase–periodic‐acid–Schiff and Ziehl–Neelsen) were negative.
