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Ri. Abe, S. Murase, Y. Nomura, K. Natsuga, Y. Tateishi, Y. Tomita, Y. Tsuji‐Abe, T. Matsumura, H. Shimizu, Acquired perforating dermatosis appearing as elastosis perforans serpiginosa and perforating folliculitis, Clinical and Experimental Dermatology, Volume 33, Issue 5, 1 September 2008, Pages 653–654, https://doi.org/10.1111/j.1365-2230.2008.02770.x
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Conflict of interest: none declared.
Acquired perforating dermatosis (APD) is an uncommon cutaneous perforating disorder, characterized clinically by hyperkeratotic papules and nodules, and histopathologically by transepidermal elimination of various substances such as keratin, collagen and elastic fibres.1 The disease arises in adulthood, usually in association with diabetes mellitus or chronic renal failure.
The clinical features and histological findings of APD may resemble any of the four classic perforating skin diseases: elastosis perforans serpiginosa (EPS), reactive perforating collagenosis, perforating folliculitis (PF) or Kyrle’s disease.2 However there have been no reports of EPS associated with any of the other three.
In this report, we present the first case, to our knowledge, of APD occurring as skin lesions including both EPS and PF types.
A 42‐year‐old Japanese woman was referred for diagnosis and treatment of skin lesions. She had presented with asymptomatic papules and erythema on the trunk 2 years previously, followed by reddish plaques on the knees 1 year previously. The skin lesions had been unresponsive to topical application of corticosteroid. Her medical history showed that she had been on dialysis for 10 years because of lupus nephritis. She had no previous history of skin disease and had not been given penicillamine.
