-
Views
-
Cite
Cite
A. Sandner, P. Helmbold, M. Winkler, S. Gattenlöhner, H.‐K. Müller‐Hermelink, H.‐J. Holzhausen, Cutaneous dissemination of nasal NK/T‐cell lymphoma in a young girl, Clinical and Experimental Dermatology, Volume 33, Issue 5, 1 September 2008, Pages 615–618, https://doi.org/10.1111/j.1365-2230.2008.02777.x
- Share Icon Share
Summary
In Europe and the USA, the incidence of primary nasal natural killer (NK)/T‐cell lymphoma is rare. The skin is one of the predilection sites for dissemination. Cutaneous dissemination is a poor prognostic sign and is consistently fatal. We describe the case of a 17‐year‐old white German girl with a primary nasal NK/T‐cell lymphoma and cutaneous dissemination. She presented with multiple maculopapular patches involving the trunk and thighs, and a 4‐week history of headache, fever and fatigue. Biopsies of the skin and the nasal mucosa were taken. Pathological examination of both specimens revealed a NK/T‐cell lymphoma. Epstein–Barr virus RNA was detected in the lymphoma cells by in situ hybridization. Unfortunately, the patient died of disease within 1 week.