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Mystery Story Mystery Story
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Think Think
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Assess Assess
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Patient: Autonomy Patient: Autonomy
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Practitioner: Beneficence and Nonmaleficence Practitioner: Beneficence and Nonmaleficence
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Public Policy: Justice Public Policy: Justice
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Conclude Conclude
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Review Questions Review Questions
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Clinical Vignettes Clinical Vignettes
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Reflection Vignettes Reflection Vignettes
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Web Links Web Links
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Cite
Abstract
Abstract:Precision medicine represents a personalized approach to healthcare, tailoring treatment and prevention strategies to individual genes, environment, and lifestyle variations. This approach often employs whole-genomic sequencing to decipher a patient’s entire DNA sequence, guiding therapeutic intervention. Predictive genomic testing assesses disease risk, diagnostic genomic testing verifies diagnoses, and pharmacogenomic testing determines appropriate medication dosages. Although promising, precision medicine raises several ethical concerns. These include complex patient autonomy issues, such as familial implications, healthcare disparities exacerbation, and privacy and confidentiality issues. Economic pressures further complicate these ethical considerations. The drive to create universal drugs, rather than personalized ones, may lead to excluding individuals at higher risk of adverse reactions. This could make drug development more profitable but result in “orphan patients” without optimal treatment options based on genetic risks. This underscores the need to consider economic and ethical factors carefully.
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