-
Views
-
Cite
Cite
Shoichiro Tomonaga, Hiroaki Ishimaru, Shizuki Misada, Takahiro Isobe, Etsuo Ohshima, Shinji Kitagaki, Synthesis and characterization of thermally stable and water-soluble pantetheine trisulfide and its composites, Bioscience, Biotechnology, and Biochemistry, Volume 89, Issue 5, May 2025, Pages 687–692, https://doi.org/10.1093/bbb/zbaf010
- Share Icon Share
Abstract
We clarified for the first time the synthesis procedure and characterization of pantetheine trisulfide, a potential new drug. Pantetheine trisulfide is the first supersulfur compound with both thermal stability and water solubility. Its hygroscopicity and deliquescence promote the hydrolysis of trisulfide, but these limitations are overcome by powdered composites of pantetheine trisulfide with silica gel or lactose.