-
Views
-
Cite
Cite
D. J. Webb, N. Benjamin, J. R. Cockcroft, J. G. Collier, Augmentation of Sympathetic Venoconstriction by Angiotensin II in Human Dorsal Hand Veins, American Journal of Hypertension, Volume 2, Issue 9, September 1989, Pages 721–723, https://doi.org/10.1093/ajh/2.9.721
- Share Icon Share
Abstract
The constriction produced by a single deep breath was measured simultaneously in two adjacent hand veins in normal subjects. One vein was infused with saline or angiotensin II; the other acted as a control. A dose of angiotensin II (1 pmol/min) that did produce venous constriction directly significantly augmented the constriction caused by deep breath in eight subjects (P < .01). In a further six subjects the same dose had no effect on venoconstriction caused by infused noradrenaline. We conclude that angiotensin II causes venoconstriction indirectly by augmenting sympathetically mediated responses, possibly by a presynaptic mechanism. Am J Hypertens 1989;2:721–723.