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David T. Malidze, Oleg S. Sychev, Vladislav N. Chubucny, Taisia V. Getman, Olga A. Epanchintseva, Helen V. Bobrova, P-642: Arterial hypertension as risk factor of development of sudden cardiac death in patients who had unstable angina in different age groups, American Journal of Hypertension, Volume 14, Issue S1, April 2001, Pages 244A–245A, https://doi.org/10.1016/S0895-7061(01)01972-0
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Abstract
The purpose of the present research was to study influence of arterial hypertension on risk of development of sudden cardiac death (SCD) at the patients, who had unstable angina (UA), in different age groups on the basis of 2 years prospective observations.
Methods: the prospective observation within 4 years was carried out over 72 elder patients (more then 65 years, group I) and 133 patients (less then 65 years group II) all male. Each group was divided into 2 subgroups (subgroup [“A”] - patients with development of SCD and subgroup [“B”]- patients without development of SCD). All patient were evalueted after clinical stabilization by daily monitoring of arterial hypertension. Arterial hypertension was compared to other SCD risk factors by multivariate regression analysis of Cox.
Results: during 2 years observations, SCD occured at 22 patients (33,3 %) in group I. At comparison of parameters of daily average systolic arterial, diastolic arterial and pulse hypertension between subgroups IA and IB of authentic differences was not observed. In group II SCD was developed at 20 patients (15,0 %). The patients of subgroup IIA, at which was developed SCD had authentically more high level daily average sistolic hypertension (145,0±9,6 mmhg), than patients without development of SCD (122±7,5 mmhg, p < 0,05, OR=2,3(1,5-2,7)).
Conclusion: the increased level of systolic arterial hypertension is an independent risk factor of development of SCD at the patients of elderly age, who had unstable angina.
