Figure 1.
DiS-C3(3) is a substrate of both ScPdr5p and KlPdr5p. (A) Intracellular accumulation of the probe in S. cerevisiae (both PDR5+ and pdr5–) and K. lactis (both PDR5+ and pdr5–) cells was imaged by confocal microscopy after 30 min incubation with the fluorescent probe. (B) Growth inhibition zones measured in a disc diffusion test; all strains were exposed to 1 mM diS-C3(3).
