Steroid metabolite excretion in ACA (n = 102) and ACC (n = 45) according to steroid classes. A, Metabolites of adrenal androgen precursors and active androgens; B, metabolites of mineralocorticoids and their precursors; C, metabolites of glucocorticoid precursors; D, cortisol and cortisone metabolites. Box plots represent median and interquartile ranges; the whiskers represent 5th and 95th percentile, respectively. *, P < 0.05; **, P < 0.01; ***, P < 0.001 comparing ACA with ACC.