Figure 3.
Bromoquinol reduces mortality in G. mellonella larvae infected with A. fumigatus. (a) Bromoquinol at a concentration of 8 mg/kg significantly (P = 0.0024) reduced mortality of Galleria larvae injected with 5 × 105 conidia of A. fumigatus. (b) Bromoquinol at a concentration of up to 8 mg/kg did not reduce mortality in immunosuppressed mice inoculated intranasally with 5 × 105 conidia of A. fumigatus. Antifungal amphotericin B was used as a positive treatment control. AMB, amphotericin B; BQ, bromoquinol.