Fig. 2.
![Pairwise alignment of CH3H and F3′H amino acid sequences from C. sulphureus (Accession nos FJ216429 and FJ216426). Alignment was performed with ClustalW (Thompson et al., 1994, 2002). Grey-shaded boxes highlight substrate recognition site 1 (SRS1: Gotoh, 1992) and conserved P450 patterns. I, Hydrophobic membrane anchor; II, proline-rich hinge [PI]-P-G-P-X-[GP]-P (Kemper, 2004); III, oxygen-binding motif [AG]-G-X-[ED]-T-[TS]; IV, EXXR triad (Ravichandran et al., 1993); V, the P450-pattern [FW]-[SNGH]-X-[GD]-{F}-[RKHPT]-{P}-C-[LIVMFAP]-[GAD] (Prosite pattern PS00086; Hulo et al., 2006).](https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/jxb/61/12/10.1093_jxb_erq169/1/jexboterq169f02_ht.gif?Expires=1750721558&Signature=M7boJJoZ6ReK3aT64-WWmwbgJa1hJQp7BKQQPWvhNKgYu1UVJ7-IPQBya8lfXm~mM70eL7nD27j0aTX~5XtjRIv-A24mJfnmDyAyYNPW4u6yqC1neeVHERPn8hKQCJqIPAiw1eADGNeEeSJbmUuE~QWjTKMicnjt3Cun9xSIk7uzCcWT5U2uuVaOlDrcv0qViPvt~SkPPzjEOGhVwsUcMwdBIWUIefgaf7LLEG~qsleEL86KOhg8KzDtGvRs7AeDKx8Xk0U-GgcI5sNO9QJWYtskTmSIld~Aos1aXRLsLkvFLY-pcOUFH55n~m4wf~dWhiyDVtU9HdY0tt4oXxJXBA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Pairwise alignment of CH3H and F3′H amino acid sequences from C. sulphureus (Accession nos FJ216429 and FJ216426). Alignment was performed with ClustalW (Thompson et al., 1994, 2002). Grey-shaded boxes highlight substrate recognition site 1 (SRS1: Gotoh, 1992) and conserved P450 patterns. I, Hydrophobic membrane anchor; II, proline-rich hinge [PI]-P-G-P-X-[GP]-P (Kemper, 2004); III, oxygen-binding motif [AG]-G-X-[ED]-T-[TS]; IV, EXXR triad (Ravichandran et al., 1993); V, the P450-pattern [FW]-[SNGH]-X-[GD]-{F}-[RKHPT]-{P}-C-[LIVMFAP]-[GAD] (Prosite pattern PS00086; Hulo et al., 2006).
