Sagittal sinus oxygen saturation, regional cerebral tissue oxygenation saturation, SVC oxygen saturation and mixed venous oxygen saturation in pigs during 34°C experimental CPB, with SVC obstruction and interventions in the form of VP respective PR of congestion. Means and SEMs. StO₂cer, SsvcO₂ and SsagO₂ were significantly lowered by SVC obstruction (all pigs). Both intervention techniques increased all three variables (StO₂cer: VP P = 0.1868, PR P = 0.0011; SsvcO₂: VP P = 0.0064, PR P = 0.0669; SsagO₂: VP P = 0.0385, PR P = 0.1163), whereas the SvO₂ results were inconsistent. PR: partial relief of congestion; SsagO₂: sagittal sinus oxygen saturation; SsvcO₂: SVC oxygen saturation; StO₂cer: cerebral tissue oxygen saturation index; SvO₂: mixed venous oxygen saturation; VP: vasopressor treatment.