Weekly rate (per 1 000 000), by age group, of laboratory-confirmed rotavirus infections reported in England and Wales, July 2000 through June 2015. Solid gray lines represent the mean weekly rate for the prevaccination era. Dashed gray lines represent the maximum and minimum weekly rate for the prevaccination era. Solid black lines represent the weekly rate for the postvaccination rotavirus season (July 2013 through June 2014). Dashed black lines represent the weekly rate for the postvaccination rotavirus season (July 2014 through June 2015).