TGFBR1 ASE distribution in 109 CRC patients and 125 controls studied by pyrosequencing. ( A ) ASE values obtained from pyrosequencing. ( B ) The same data shown after ASE values <1.0 have been transformed to their reciprocals. Superscript numerals with probability values refer to the following: 1, Paired Wilcoxon test; 2, permutation test comparing means; and 3, permutation test comparing medians.