Changes in methionine-related metabolite levels in the leaves of mam1 and mam3. Metabolite contents were analyzed in six replicates. Fold change of the average metabolite content in the knockout line with respect to that in the wild type is shown. P-values of Welch’s t-test are also shown. When P < 0.05, the fold change column is colored as follows: red, fold change >2; blue, fold change <0.5; gray, 0.5 ≤ fold change ≤ 2.