The GDDG mutation does not change the fold of the KH domain. Superimposition of ¹ H– ¹⁵ N correlation spectra of wild-type (cyan) and mutant (orange) for the KH1, KH2, KH3, KH4 domains of KSRP and KH34 di-domain of ZBP1 proteins. The limited changes we observe confirm that the domains maintain their folded state.