RFS and OS of all patients in relation to EGFR mutation status (n = 379). (A) The 3- and 5-year RFS rates of patients with and without EGFR mutation were 77 and 70% and 64 and 55%, respectively. These survival curves were significantly different (P = 0.003). (B) The 3- and 5-year OS rates of patients with and without EGFR mutation were 92 and 87% and 80 and 72%, respectively. These survival curves were also significantly different (P < 0.001). RFS: recurrence-free survival; OS: overall survival; EGFR: epidermal growth factor receptor.