Hcy induces the M2 to M1 phenotype switch. (a) Comparison of the mRNA expression of various inflammatory factors in the mouse visceral adipose tissue using reverse transcription quantitative PCR (n = 8). (b) The percentage of M1 and M2 macrophages in the mouse visceral adipose tissue using fluorescence-activated cell-sorting measurement (n = 5). (c) Comparison of the protein levels of (d) Arg1, (e) iNOS, and (f) pAkt/tAkt in the mouse visceral adipose tissue using Western blot analysis (n = 8). *P < 0.05, one-way analysis of variance, with Tukey’s post hoc test. Ctl, control.